Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4038446 | 1.00 | KMT2A (0.43) | KMT2AMEN1NPC1MAPTNPSR1 | |
| SCHEMBL4035456 | 0.86 | KMT2A (0.42) | KMT2AMEN1NPC1MAPTNPSR1 | |
| SCHEMBL4035465 | 0.86 | KMT2A (0.42) | KMT2AMEN1NPC1MAPTNPSR1 | |
| SCHEMBL4032288 | 0.85 | KMT2A (0.41) | KMT2AMEN1NPC1MAPTNPSR1 | |
| SCHEMBL4032286 | 0.85 | KMT2A (0.41) | KMT2AMEN1NPC1MAPTNPSR1 | |
| SCHEMBL4037079 | 0.84 | KMT2A (0.40) | KMT2AMEN1MAPTNPSR1TDP1 | |
| SCHEMBL4037068 | 0.84 | KMT2A (0.40) | KMT2AMEN1MAPTNPSR1TDP1 | |
| SCHEMBL4034834 | 0.83 | MEN1 (0.39) | KMT2AMEN1MAPTTDP1SSTR2 | |
| SCHEMBL4034832 | 0.83 | MEN1 (0.39) | KMT2AMEN1MAPTTDP1SSTR2 | |
| SCHEMBL4032356 | 0.83 | KMT2A (0.47) | KMT2AMEN1NPC1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019102-A1 | Alkylacetylene substituted Acyltryptophanols | Bayer Schering Pharma AG (DE) | 2009-01-28 | — | — | EP | disclosed |