Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541280 | 0.87 | CCR3 (0.45) | LMNAMEN1KMT2ACCR3POLB | |
| SCHEMBL2086372 | 0.83 | MEN1 (0.45) | LMNATHRBGPR119MEN1KMT2A | |
| SCHEMBL2086585 | 0.82 | MEN1 (0.43) | LMNATHRBGPR119MEN1KMT2A | |
| SCHEMBL2084109 | 0.82 | MEN1 (0.41) | LMNATHRBGPR119MEN1KMT2A | |
| SCHEMBL2084361 | 0.81 | MEN1 (0.45) | LMNATHRBGPR119MEN1KMT2A | |
| SCHEMBL2083960 | 0.80 | CXCR4 (0.45) | LMNATHRBGPR119MEN1KMT2A | |
| SCHEMBL4030263 | 0.78 | SLC6A2 (0.46) | POLB | |
| SCHEMBL2082179 | 0.78 | GPR119 (0.51) | GPR119MEN1KMT2APOLB | |
| SCHEMBL2084212 | 0.78 | MEN1 (0.44) | LMNAGPR119MEN1KMT2ATP53 | |
| SCHEMBL2083669 | 0.78 | MEN1 (0.44) | LMNATHRBGPR119MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613613-B1 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORP (US) | 2021-06-02 | — | — | EP | disclosed |
| EP-1613613-A4 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC (CA) | 2009-03-25 | — | — | EP | disclosed |
| EP-1613613-A2 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004091518-A2 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2004-10-28 | — | — | WO | disclosed |