SCHEMBL4039347

SCHEMBL4039347

C1=CC(O[SiH2]c2cccc3c2Cc2ccccc2-3)c2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.35
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28363748 0.78 PNMT (0.37) PNMTNPC1RAB9A
SCHEMBL5823610 0.73 PNMT (0.41) PNMTNPC1RAB9A
SCHEMBL8053261 0.70 PNMT (0.40) PNMTNPC1RAB9A
Hydrochloric Acid SCHEMBL673539 0.69 PNMT (0.36) PNMTNPC1RAB9A
Hydrochloric Acid SCHEMBL29911898 0.69 PNMT (0.36) PNMTNPC1RAB9A
SCHEMBL5981622 0.68 PNMT (0.52) PNMTNPC1RAB9A
SCHEMBL30569491 0.68 PNMT (0.52) PNMTNPC1RAB9A
SCHEMBL7638914 0.68 PNMT (0.50) PNMTNPC1RAB9A
SCHEMBL566027 0.68 PNMT (0.37) PNMTNPC1RAB9A
SCHEMBL30534985 0.68 PNMT (0.37) PNMTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009149906-A2 PREPARATION OF SILOXY-BRIDGED METALLOCENES BASELL POLYOLEFINE GMBH (DE) 2009-12-17 WO disclosed
US-7544825-B1 Preparation of siloxy-bridged metallocenes BASELL POLYOLEFINE GMBH (DE) 2009-06-09 US disclosed