Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21326206 | 0.87 | PNMT (0.37) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL7778428 | 0.85 | PNMT (0.35) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL29606694 | 0.84 | PNMT (0.35) | PNMTNPC1RAB9A | |
| SCHEMBL2968923 | 0.81 | MAOA (0.35) | NPC1RAB9AHTR2BHTR2AMAOA | |
| SCHEMBL30534985 | 0.76 | PNMT (0.37) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL29987276 | 0.76 | PNMT (0.37) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL7638914 | 0.76 | PNMT (0.50) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL8053261 | 0.76 | PNMT (0.40) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL566027 | 0.76 | PNMT (0.37) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL28363748 | 0.76 | PNMT (0.37) | PNMTNPC1RAB9AHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106905133-B | Spiro-fluorene-indene diketone compound and preparation method and application thereof | 肇庆医学高等专科学校 | 2020-06-19 | — | — | CN | claimed |
| CN-116444435-B | Fluorene derivative, electronic element and electronic device | 浙江八亿时空先进材料有限公司 | 2024-05-24 | — | — | CN | disclosed |
| US-11818908-B2 | Thin film electroluminescent device, preparation method thereof, and electronic device | WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) | 2023-11-14 | — | — | US | disclosed |
| CN-106905133-B | Spiro-fluorene-indene diketone compound and preparation method and application thereof | 肇庆医学高等专科学校 | 2020-06-19 | — | — | CN | disclosed |
| WO-2006126776-A1 | ANTIREFLECTIVE HARDMASK COMPOSITION AND METHODS FOR USING SAME | CHEIL INDUSTRIES INC. (KR) | 2006-11-30 | — | — | WO | disclosed |
| US-20060269867-A1 | Antireflective hardmask composition and methods for using same | CHEIL INDUSTRIES, INC. (KR) | 2006-11-30 | — | — | US | disclosed |