Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.50 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4036808 | 0.86 | DAO (0.51) | DAOATAD2HRH4CNR2DRD3 | |
| SCHEMBL27631818 | 0.84 | DAO (0.50) | DAOATAD2HRH4CNR2DRD3 | |
| SCHEMBL4039329 | 0.80 | ATAD2 (0.49) | DAOATAD2HRH4CNR2MEN1 | |
| SCHEMBL27738193 | 0.78 | DAO (0.51) | DAOATAD2HRH4CNR2MEN1 | |
| SCHEMBL29362530 | 0.76 | HRH4 (0.56) | DAOATAD2HRH4CNR2DRD3 | |
| SCHEMBL1194081 | 0.76 | HRH4 (0.56) | DAOATAD2HRH4CNR2DRD3 | |
| SCHEMBL3092620 | 0.75 | ATAD2 (0.53) | DAOATAD2HRH4DRD3MAPT | |
| Bromide SCHEMBL31707091 | 0.74 | HRH4 (0.55) | DAOATAD2HRH4CNR2DRD3 | |
| Bromide SCHEMBL31706580 | 0.74 | HRH4 (0.55) | DAOATAD2HRH4CNR2DRD3 | |
| SCHEMBL3836490 | 0.73 | FLT3 (0.50) | DAOMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747220-B1 | SUBSTITUTED 1H-PYRROLO[3,2-B, 3,2-C, AND 2,3-C]PYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I EPSILON | AVENTIS PHARMA INC (US) | 2009-04-15 | — | — | EP | claimed |