Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196580 | 0.85 | ALDH1A1 (0.50) | ALDH1A1HTTKMT2ALMNAMAPT | |
| SCHEMBL27625586 | 0.85 | ALDH1A1 (0.50) | ALDH1A1HTTKMT2ALMNAMAPT | |
| SCHEMBL15881094 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HTTKMT2ALMNAMAPT | |
| SCHEMBL11024647 | 0.82 | LMNA (0.38) | ALDH1A1HTTKMT2ALMNAMAPT | |
| SCHEMBL9193139 | 0.82 | ALDH1A1 (0.55) | ALDH1A1HTTKMT2ALMNAMAPT | |
| SCHEMBL2924595 | 0.81 | KMT2A (0.50) | ALDH1A1HTTKMT2ALMNAMAPT | |
| SCHEMBL9191930 | 0.81 | KMT2A (0.57) | ALDH1A1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL9413739 | 0.77 | LCK (0.40) | ALDH1A1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL9191924 | 0.76 | LMNA (0.50) | ALDH1A1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL9196209 | 0.76 | KMT2A (0.47) | ALDH1A1KMT2ALMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066637-A1 | NOVEL SUBSTITUTED BIPYRIDINE DERIVATIVES AND THEIR USE AS ADENOSINE RECEPTOR LIGANDS | Bayer HealthCare AG (DE) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008028590-A1 | NOVEL SUBSTITUTED BIPYRIDINE DERIVATIVES AND THEIR USE AS ADENOSINE RECEPTOR LIGANDS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | disclosed |
| EP-0497851-B1 | SULPHONATED HETEROCYCLIC CARBOXAMIDES AS HERBICIDES, GROWTH REGULATORS OR FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-01-04 | — | — | EP | disclosed |
| EP-0497851-A1 | SULPHONATED HETEROCYCLIC CARBOXAMIDES AS HERBICIDES, GROWTH REGULATORS OR FUNGICIDES. | HOECHST AG (DE) | 1992-08-12 | — | — | EP | disclosed |
| WO-1991006541-A1 | SULPHONATED HETEROCYCLIC CARBOXAMIDES AS HERBICIDES, GROWTH REGULATORS OR FUNGICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-16 | — | — | WO | disclosed |