Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 2/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041125 | 0.91 | CTSK (0.35) | CTSK | |
| SCHEMBL4045130 | 0.90 | DPP4 (0.46) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL4052756 | 0.88 | DPP4 (0.38) | DPP4CTSKFAPDPP8DPP9 | |
| SCHEMBL4052736 | 0.87 | CTSK (0.34) | DPP4CTSKFAPDPP8DPP9 | |
| SCHEMBL4045397 | 0.86 | CTSK (0.34) | CTSK | |
| SCHEMBL4044235 | 0.86 | CTSK (0.35) | DPP4CTSKDPP8DPP9 | |
| SCHEMBL4043687 | 0.85 | CTSK (0.40) | CTSK | |
| SCHEMBL4047580 | 0.85 | CTSK (0.38) | CTSK | |
| SCHEMBL4045288 | 0.85 | DPP4 (0.41) | DPP4CTSKFAPDPP8DPP9 | |
| SCHEMBL4050899 | 0.84 | DPP4 (0.40) | DPP4CTSKFAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010543-A1 | DIBENZYLIDENE SORBITOL (DBS)-BASED COMPOUNDS, COMPOSITIONS AND METHODS FOR USING SUCH COMPOUNDS | Milliken&Company (US) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007127067-A1 | DIBENZYLIDENE SORBITOL (DBS)-BASED COMPOUNDS, COMPOSITIONS AND METHODS FOR USING SUCH COMPOUNDS | MILLIKEN & COMPANY (US) | 2007-11-08 | — | — | WO | disclosed |