Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 4/20 | 0.32 |
| ▸ | FAP | Q12884 | 2/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046991 | 0.91 | CTSK (0.34) | CTSK | |
| SCHEMBL4045130 | 0.87 | DPP4 (0.46) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL4040620 | 0.87 | DPP4 (0.34) | CTSKDPP4FAPDPP8DPP9 | |
| SCHEMBL4052756 | 0.85 | DPP4 (0.38) | CTSKDPP4FAPDPP8DPP9 | |
| SCHEMBL4049033 | 0.85 | CTSK (0.33) | CTSK | |
| SCHEMBL4050242 | 0.84 | CTSK (0.36) | CTSK | |
| SCHEMBL4045379 | 0.84 | CTSK (0.38) | CTSK | |
| SCHEMBL4044235 | 0.83 | CTSK (0.35) | CTSKDPP4DPP8DPP9 | |
| SCHEMBL4050554 | 0.83 | CTSK (0.34) | CTSK | |
| SCHEMBL4045799 | 0.82 | CTSK (0.35) | CTSKDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |