Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035266 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HTTLMNAGLAPKM | |
| SCHEMBL4037945 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HTTLMNAGLAPKM | |
| SCHEMBL4033038 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HTTLMNAGLAPKM | |
| SCHEMBL4041721 | 0.89 | GAA (0.51) | ALDH1A1HTTLMNAGLAPKM | |
| SCHEMBL4041974 | 0.89 | GAA (0.51) | ALDH1A1HTTLMNAGLAPKM | |
| SCHEMBL4036675 | 0.89 | ALDH1A1 (0.51) | ALDH1A1GAACHRM5USP2 | |
| SCHEMBL4034808 | 0.89 | GAA (0.51) | ALDH1A1HTTLMNAGLAPKM | |
| SCHEMBL4035166 | 0.87 | ALDH1A1 (0.51) | ALDH1A1HTTLMNAGLAPKM | |
| SCHEMBL4033037 | 0.87 | SMN1; SMN2 (0.49) | ALDH1A1HTTLMNAGLAPKM | |
| SCHEMBL4035900 | 0.87 | SMN1; SMN2 (0.49) | ALDH1A1HTTLMNAGLAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |