Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043100 | 0.94 | HCAR2 (0.33) | HCAR2FBP1NPC1 | |
| SCHEMBL1188701 | 0.70 | — | — | |
| SCHEMBL29774205 | 0.66 | TDP1 (0.39) | HCAR2NPC1 | |
| SCHEMBL15367481 | 0.65 | TDP1 (0.41) | HCAR2NPC1 | |
| SCHEMBL31751932 | 0.64 | TDP1 (0.44) | HCAR2NPC1 | |
| SCHEMBL7519075 | 0.62 | TDP1 (0.39) | HCAR2 | |
| SCHEMBL14989194 | 0.62 | PTGS1 (0.47) | — | |
| SCHEMBL14989303 | 0.62 | PTGS1 (0.42) | — | |
| SCHEMBL3392295 | 0.61 | ALDH1A1 (0.36) | HCAR2FBP1 | |
| SCHEMBL2570414 | 0.60 | GRIA1 (0.43) | HCAR2FBP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069334-A1 | Pyridazine based alpha-helix mimetics | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-03-12 | — | — | US | disclosed |
| WO-2009025751-A1 | PYRIDAZINE BASED ALPHA-HELIX MIMETICS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069334-A1 | Pyridazine based alpha-helix mimetics | H1-4, H1-5, H1-0 | HCAR2 1606/4885FBP1 1723/4885NPC1 4517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.