Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 19/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13407407 | 1.00 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL4507055 | 1.00 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL14498893 | 0.89 | KCNH2 (0.67) | KCNH2 | |
| SCHEMBL5261640 | 0.89 | KCNH2 (0.67) | KCNH2 | |
| SCHEMBL13407409 | 0.85 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL3574972 | 0.85 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL4041610 | 0.84 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL3281423 | 0.83 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL3281428 | 0.83 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL3281435 | 0.83 | KCNH2 (0.45) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114965357-A | Methyl ethyl alkane double-gas detection method and device based on TDLAS | 北京航天控制仪器研究所 | 2022-08-30 | — | — | CN | claimed |
| US-20100081650-A1 | Antimicrobial Compounds | AXTEN JEFFREY MICHAEL | 2010-04-01 | — | — | US | claimed |
| EP-1537123-B1 | AMINO-SUBSTITUTED CYCLOHEXANE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | GLAXO GROUP LTD (GB) | 2009-04-29 | — | — | EP | claimed |
| US-20190160092-A1 | Advanced Functional Biocompatible Polymeric Matrix Used as a Hemostatic Agent and System for Damaged Tissues and Cells | UNIVERSITY OF MARYLAND, BALTIMORE | 2019-05-30 | — | — | US | disclosed |
| US-10179145-B2 | Advanced functional biocompatible polymeric matrix used as a hemostatic agent and system for damaged tissues and cells | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2019-01-15 | — | — | US | disclosed |
| US-20170326169-A1 | Advanced functional biocompatible polymeric matrix containing nano-compartments | UNIV MARYLAND (US) | 2017-11-16 | — | — | US | disclosed |
| US-20160206777-A1 | ADVANCED FUNCTIONAL BIOCOMPATIBLE POLYMERIC MATRIX USED AS A HEMOSTATIC AGENT AND SYSTEM FOR DAMAGED TISSUES AND CELLS | UNIVERSITY OF MARYLAND, COLLEGE PARK | 2016-07-21 | — | — | US | disclosed |
| US-8932560-B2 | Advanced functional biocompatible polymeric matrix used as a hemostatic agent and system for damaged tissues and cells | University of Maryland, College Parke (US) | 2015-01-13 | — | — | US | disclosed |
| US-20100081650-A1 | Antimicrobial Compounds | AXTEN JEFFREY MICHAEL | 2010-04-01 | — | — | US | disclosed |
| US-7622481-B2 | Antibacterial compounds | GLAXO GROUP LIMITED (GB) | 2009-11-24 | — | — | US | disclosed |
| US-20090062849-A1 | Advanced functional biocompatible polymeric matrix used as a hemostatic agent and system for damaged tissues and cells | UNIVERSITY OF MARYLAND, BALTIMORE | 2009-03-05 | — | — | US | disclosed |
| US-20060189604-A1 | Compounds | GLAXO GROUP LIMITED (GB) | 2006-08-24 | — | — | US | disclosed |
| EP-1537123-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004002992-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2004-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10179145-B2 | Advanced functional biocompatible polymeric matrix used as a hemostatic agent and system for damaged tissues and cells | PLAT, FGB, PLG | KCNH2 2633/4885 |
| US-20170326169-A1 | Advanced functional biocompatible polymeric matrix containing nano-compartments | CHMP4B, CD63, EXOSC5 | KCNH2 3810/4885 |
| US-20060189604-A1 | Compounds | ELANE, PIGS, SDHA | KCNH2 2854/4885 |
| US-20190160092-A1 | Advanced Functional Biocompatible Polymeric Matrix Used as a Hemostatic Agent and System for Damaged Tissues and Cells | PLAT, FGB, PLG | KCNH2 2633/4885 |
| US-20100081650-A1 | Antimicrobial Compounds | ELANE, NISCH, PIGS | KCNH2 3731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.