Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4497830 | 0.88 | TRPV1 (0.43) | TRPV1 | |
| SCHEMBL3572972 | 0.88 | TRPV1 (0.43) | TRPV1 | |
| SCHEMBL5260210 | 0.76 | PDGFRB (0.41) | — | |
| SCHEMBL5264336 | 0.76 | KCNH2 (0.52) | — | |
| SCHEMBL5260758 | 0.72 | HTT (0.49) | TRPV1 | |
| SCHEMBL5263446 | 0.72 | HTT (0.49) | TRPV1 | |
| SCHEMBL5252685 | 0.71 | HTT (0.47) | TRPV1 | |
| SCHEMBL4043254 | 0.69 | KCNH2 (0.46) | — | |
| SCHEMBL5503903 | 0.69 | HTT (0.46) | — | |
| SCHEMBL30114438 | 0.68 | TRPV1 (0.64) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537123-B1 | AMINO-SUBSTITUTED CYCLOHEXANE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | GLAXO GROUP LTD (GB) | 2009-04-29 | — | — | EP | claimed |