SCHEMBL404199

SCHEMBL404199

Cc1ccc2nc(Cl)c(Cl)nc2c1

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 1/20 0.64
ALDH1A1 P00352 5/20 0.56
KDM4E B2RXH2 6/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
KMT2A Q03164 3/20 0.53
NPSR1 Q6W5P4 1/20 0.53
MAPT P10636 5/20 0.52
TDP1 Q9NUW8 2/20 0.52
LMNA P02545 1/20 0.48
MEN1 O00255 2/20 0.47
PABPC1 P11940 1/20 0.47
CYP1A2 P05177 2/20 0.46
RAB9A P51151 2/20 0.46
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
MPI P34949 1/20 0.43
NCK1 P16333 1/20 0.42
BACE1 P56817 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14764426 0.89 NQO2 (0.57) NQO2ALDH1A1KDM4EL3MBTL1KMT2A
SCHEMBL14764615 0.89 NQO2 (0.57) NQO2ALDH1A1KDM4EL3MBTL1KMT2A
SCHEMBL1138054 0.86 NQO2 (0.53) NQO2ALDH1A1KDM4EL3MBTL1KMT2A
SCHEMBL13077444 0.86 NQO2 (0.53) NQO2ALDH1A1KDM4EL3MBTL1KMT2A
SCHEMBL2756741 0.85 NQO2 (0.85) NQO2ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL9927345 0.85 NQO2 (0.85) NQO2ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL20049288 0.82 ALDH1A1 (0.50) NQO2ALDH1A1KDM4EL3MBTL1KMT2A
SCHEMBL29340312 0.82 PGK1 (0.57) NQO2ALDH1A1KDM4EL3MBTL1KMT2A
SCHEMBL4928778 0.82 NQO2 (0.50) NQO2ALDH1A1KDM4EL3MBTL1KMT2A
SCHEMBL29340314 0.82 PGK1 (0.57) NQO2ALDH1A1KDM4EL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798283-A All-organic water system zinc ion battery positive electrode material and preparation method and application thereof 石河子大学 2025-04-11 CN claimed
US-20090274967-A1 QUINOXALINE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-11-05 US claimed
EP-0266662-B1 PROCESS FOR THE PREPARATION OF POLY(ARYLENSULPHIDES) WITH LOWER CRYSTALLIZATION TEMPERATURE BAYER AG (DE) 1992-06-10 EP claimed
US-4824933-A DIMENSIONAL STABILITY, CHEMICAL RESISTANT BAYER AKTIENGESELLSCHAFT (DE) 1989-04-25 US claimed
EP-0266662-A2 Process for the preparation of poly(arylensulphides) with lower crystallization temperature BAYER AG (DE) 1988-05-11 EP claimed
CN-119798283-A All-organic water system zinc ion battery positive electrode material and preparation method and application thereof 石河子大学 2025-04-11 CN disclosed
WO-2025021868-A1 TRAF2 INHIBITORS FOR THE TREATMENT OF CANCER AND OTHER DISEASES Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) 2025-01-30 WO disclosed
WO-2022202643-A1 METHOD FOR PRODUCING S,S-(6-METHYLQUINOXALINE-2,3-DIYL)DITHIOCARBONATE 株式会社大阪ソーダ 2022-09-29 WO disclosed
US-11299634-B2 Reactive leuco compounds and compositions comprising the same MILLIKEN & COMPANY (US) 2022-04-12 US disclosed
CN-107935944-B Diaryl urea quinoxaline derivative with anti-tumor activity and synthetic method thereof 广西师范大学 2021-12-21 CN disclosed
US-11028090-B2 [1,2,4]Triazolo[4,3-a]quinoxaline derivative, method for preparing same, and pharmaceutical composition for preventing or treating BET protein-related diseases, containing same as active ingredient DONG WHA PHARM. CO., LTD. (KR) 2021-06-08 US disclosed
US-11028090-B2 [1,2,4]Triazolo[4,3-a]quinoxaline derivative, method for preparing same, and pharmaceutical composition for preventing or treating BET protein-related diseases, containing same as active ingredient DONG WHA PHARM. CO., LTD. (KR) 2021-06-08 US disclosed
EP-0095637-A2 Process for preparing alpha-chlorinated nitrogen heterocycles BAYER AG (DE) 1983-12-07 EP disclosed
EP-0045423-A1 Process for the alpha-halogenation of possibly substituted methyl aromatics BAYER AG (DE) 1982-02-10 EP disclosed
US-4200748-A ANXIOLYTIC AGENTS AMERICAN CYANAMID COMPANY (US) 1980-04-29 US disclosed
US-4184977-A WHITENING BAYER AKTIENGESELLSCHAFT (DE) 1980-01-22 US disclosed
EP-0000346-B1 QUINOXALINE COMPOUNDS, PROCESS FOR THEIR MANUFACTURE AND THEIR USE AS BRIGHTENERS FOR ORGANIC MATERIALS, AND THE MATERIALS BRIGHTENED THEREWITH BAYER AG (DE) 1980-01-09 EP disclosed
EP-0000346-A1 Quinoxaline compounds, process for their manufacture and their use as brighteners for organic materials, and the materials brightened therewith BAYER AG (DE) 1979-01-24 EP disclosed
US-4025510-A DYES FOR POLYESTERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-05-24 US disclosed
US-3988455-A Ditetrazolo(1,5-a:5',1'-c)quinoxalines for control of soil-borne phytopathogens ELI LILLY AND COMPANY (US) 1976-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11028090-B2 [1,2,4]Triazolo[4,3-a]quinoxaline derivative, method for preparing same, and pharmaceutical composition for preventing or treating BET protein-related diseases, containing same as active ingredient BRD4, BET1, BRD3 NQO2 486/4885ALDH1A1 4699/4885KDM4E 210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.