Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 4/20 | 0.46 |
| ▸ | MMP2 | P08253 | 4/20 | 0.45 |
| ▸ | MMP3 | P08254 | 4/20 | 0.45 |
| ▸ | MMP9 | P14780 | 4/20 | 0.45 |
| ▸ | MMP13 | P45452 | 4/20 | 0.45 |
| ▸ | MMP1 | P03956 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1843118 | 1.00 | GPR139 (0.46) | GPR139MMP2MMP3MMP9MMP13 | |
| SCHEMBL4566787 | 0.92 | GPR139 (0.47) | GPR139MMP2MMP3MMP9MMP13 | |
| SCHEMBL4566786 | 0.92 | GPR139 (0.47) | GPR139MMP2MMP3MMP9MMP13 | |
| SCHEMBL1842858 | 0.92 | GPR139 (0.47) | GPR139MMP2MMP3MMP9MMP13 | |
| SCHEMBL4210499 | 0.92 | MMP2 (0.49) | GPR139MMP2MMP3MMP9MMP13 | |
| SCHEMBL379315 | 0.92 | MMP2 (0.49) | GPR139MMP2MMP3MMP9MMP13 | |
| SCHEMBL1841931 | 0.92 | MMP2 (0.49) | GPR139MMP2MMP3MMP9MMP13 | |
| SCHEMBL1845723 | 0.91 | GPR139 (0.40) | GPR139MMP2MMP3MMP9MMP13 | |
| SCHEMBL1840352 | 0.91 | MMP2 (0.36) | GPR139MMP2MMP3MMP9MMP13 | |
| SCHEMBL4038095 | 0.90 | MMP2 (0.49) | GPR139MMP2MMP3MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074093-A2 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008023336-A2 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2008-02-28 | — | — | WO | disclosed |