Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041458 | 0.89 | LCK (0.53) | LCK | |
| SCHEMBL4036109 | 0.87 | LCK (0.46) | LCK | |
| SCHEMBL4041724 | 0.85 | LCK (0.42) | LCK | |
| SCHEMBL4041184 | 0.85 | LCK (0.55) | LCKFGFR1 | |
| SCHEMBL4037163 | 0.84 | FGFR1 (0.43) | LCKFGFR1 | |
| SCHEMBL4042434 | 0.82 | LCK (0.41) | LCKFGFR1 | |
| SCHEMBL4036362 | 0.81 | LCK (0.41) | LCKFGFR1 | |
| SCHEMBL6626585 | 0.74 | LCK (0.45) | LCK | |
| SCHEMBL6644633 | 0.72 | IKBKB (0.37) | LCK | |
| SCHEMBL4042263 | 0.71 | LCK (0.47) | LCKFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066286-B1 | HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2009-04-29 | — | — | EP | claimed |
| EP-1066286-B1 | HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2009-04-29 | — | — | EP | disclosed |