Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 7/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL644475 | 0.94 | NPC1 (0.69) | PKMRAB9ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL1667825 | 0.84 | RAB9A (0.73) | PKMRAB9ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL11241115 | 0.83 | RAB9A (0.75) | PKMRAB9ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL9265040 | 0.81 | RAB9A (0.79) | PKMRAB9ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL6707186 | 0.81 | RAB9A (0.79) | PKMRAB9ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL28149234 | 0.81 | PKM (0.67) | PKMRAB9ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL23384768 | 0.79 | SMYD3 (0.76) | PKMRAB9ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL2539899 | 0.78 | NPC1 (0.71) | PKMRAB9ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL2468483 | 0.78 | NPC1 (0.71) | PKMRAB9ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL14748632 | 0.78 | SMYD3 (0.74) | PKMRAB9ASMN1; SMN2HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2020404-A1 | Cyanomethyl substituted N-Acyl Tryptamines | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-02-04 | — | — | EP | disclosed |