Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.73 |
| ▸ | PPARG | P37231 | 12/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PPARD | Q03181 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | FABP2 | P12104 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11738947 | 0.86 | PPARG (0.72) | PPARAPPARGMEN1CYP1A2CYP3A4 | |
| SCHEMBL3845467 | 0.85 | PPARA (1.00) | PPARAPPARGMEN1CYP1A2CYP3A4 | |
| SCHEMBL1009896 | 0.83 | PPARA (0.73) | PPARAPPARGMEN1CYP1A2CYP3A4 | |
| SCHEMBL4036404 | 0.82 | PPARG (0.66) | PPARAPPARGMEN1CYP1A2CYP3A4 | |
| SCHEMBL4036197 | 0.82 | PPARG (0.66) | PPARAPPARGMEN1CYP1A2CYP3A4 | |
| SCHEMBL4033331 | 0.82 | PPARA (0.66) | PPARAPPARGMEN1CYP1A2CYP3A4 | |
| SCHEMBL2558984 | 0.82 | PPARA (0.71) | PPARAPPARGMEN1CYP1A2CYP3A4 | |
| SCHEMBL3839840 | 0.82 | PPARA (1.00) | PPARAPPARGMEN1CYP1A2CYP3A4 | |
| SCHEMBL4034371 | 0.81 | PPARA (0.69) | PPARAPPARGMEN1CYP1A2CYP3A4 | |
| SCHEMBL1349983 | 0.81 | PPARA (0.64) | PPARAPPARGCYP1A2CYP3A4PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049107-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | Genfit (FR) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |
| EP-0621255-B1 | Substituted phenoxy-isobutyric acids and esters | ADIR (FR) | 1997-08-20 | — | — | EP | disclosed |
| EP-0621255-A1 | Substituted phenoxy-isobutyric acids and esters | ADIR ET COMPAGNIE (FR) | 1994-10-26 | — | — | EP | disclosed |