Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.72 |
| ▸ | PPARA | Q07869 | 12/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | PPARD | Q03181 | 5/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.54 |
| ▸ | FABP2 | P12104 | 1/20 | 0.53 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4036404 | 0.95 | PPARG (0.66) | PPARGPPARAMEN1CYP1A2CYP3A4 | |
| SCHEMBL4033331 | 0.95 | PPARA (0.66) | PPARGPPARAMEN1CYP1A2CYP3A4 | |
| SCHEMBL4036197 | 0.95 | PPARG (0.66) | PPARGPPARAMEN1CYP1A2CYP3A4 | |
| SCHEMBL4033117 | 0.91 | PPARA (0.60) | PPARGPPARAMEN1CYP1A2CYP3A4 | |
| SCHEMBL4042833 | 0.86 | PPARA (0.73) | PPARGPPARAMEN1CYP1A2CYP3A4 | |
| SCHEMBL4036545 | 0.84 | PPARG (0.60) | PPARGPPARAMEN1CYP1A2CYP3A4 | |
| SCHEMBL9996916 | 0.84 | PPARG (1.00) | PPARGPPARAMEN1CYP1A2CYP3A4 | |
| SCHEMBL10289687 | 0.84 | PPARG (0.74) | PPARGPPARAMEN1CYP1A2CYP3A4 | |
| SCHEMBL14122275 | 0.83 | PPARA (0.50) | PPARGPPARAMEN1CYP1A2CYP3A4 | |
| SCHEMBL5795917 | 0.82 | PPARG (0.72) | PPARGPPARAMEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532123-A | Thiazole-5-methanamide compound and preparation method, medicinal composition and application thereof | INST MATERIA MEDICA CAMS | 2012-07-04 | — | — | CN | disclosed |
| US-4039683-A | PHENOXYPROPIONIC ACID DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-08-02 | — | — | US | disclosed |
| US-3968143-A | Phenoxypropionic acid derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-07-06 | — | — | US | disclosed |