Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.57 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CCR1 | P32246 | 1/20 | 0.54 |
| ▸ | CCR2 | P41597 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ACLY | P53396 | 1/20 | 0.49 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.48 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2897956 | 0.89 | CCR1 (0.60) | PTGDR2CACNA1HCACNA1BPOLBCCR1 | |
| SCHEMBL3274401 | 0.87 | POLB (0.72) | PTGDR2CACNA1HCACNA1BPOLBCCR1 | |
| SCHEMBL3050790 | 0.82 | PTPN1 (0.61) | CACNA1HCACNA1BCCR1CCR2TDP1 | |
| SCHEMBL3047854 | 0.82 | PTGDR2 (0.57) | PTGDR2CACNA1HCACNA1BPOLBCCR1 | |
| SCHEMBL3148243 | 0.81 | CCR2 (0.70) | CCR1CCR2 | |
| SCHEMBL3054749 | 0.81 | CCR1 (0.54) | PTGDR2CACNA1HCACNA1BPOLBCCR1 | |
| SCHEMBL3050536 | 0.81 | CACNA1H (0.62) | CACNA1HCACNA1BCCR1CCR2TDP1 | |
| SCHEMBL8752434 | 0.81 | FFAR1 (0.65) | PTGDR2CACNA1HCACNA1BPOLBTDP1 | |
| SCHEMBL3049521 | 0.80 | POLB (0.53) | PTGDR2CACNA1HCACNA1BPOLBCCR1 | |
| SCHEMBL2901147 | 0.80 | CACNA1H (0.51) | PTGDR2CACNA1HCACNA1BPOLBCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2076491-A1 | NEW BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | Richter Gedeon NYRT (HU) | 2009-07-08 | — | — | EP | disclosed |
| WO-2008068540-A1 | NEW BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2008-06-12 | — | — | WO | disclosed |