Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL405980 | 0.92 | F7 (0.42) | F7F3DYRK1ANR4A2PIK3CG | |
| SCHEMBL4742084 | 0.76 | MAPK13 (0.37) | DYRK1A | |
| SCHEMBL405781 | 0.75 | HTT (0.38) | ALDH1A1MAPTTDP1HTTCYP1A2 | |
| SCHEMBL2305037 | 0.75 | NQO2 (0.42) | ALDH1A1PARP1RAB9AKDM4EMEN1 | |
| SCHEMBL406463 | 0.71 | KDM4E (0.43) | DYRK1APARP1KDM4E | |
| SCHEMBL1973 | 0.70 | MAPT (0.36) | ALDH1A1KDM4EHSD17B10MAPTTDP1 | |
| SCHEMBL780179 | 0.70 | NR4A2 (0.56) | F7F3DYRK1ANR4A2PIK3CG | |
| SCHEMBL209220 | 0.69 | SMN1; SMN2 (0.32) | RAB9ANPC1FGFR3KDRPDGFRB | |
| SCHEMBL2511032 | 0.69 | — | — | |
| Bromide SCHEMBL11411808 | 0.69 | NR4A2 (0.54) | F7F3DYRK1ANR4A2PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389066-B1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LTD (GB) | 2017-07-05 | — | — | EP | claimed |
| EP-2387569-B1 | HERBCIDES | SYNGENTA LTD (GB) | 2016-06-15 | — | — | EP | claimed |
| US-8895474-B2 | Herbicidally active cyclopentanediones and derivatives thereof, and their use in controlling weeds | SYNGENTA LIMITED (GB) | 2014-11-25 | — | — | US | claimed |
| US-8865623-B2 | Herbicidally active cyclic diones and derivatives thereof, processes for their preparation, compositions, and method of controlling weeds | SYNGENTA LIMITED (GB) | 2014-10-21 | — | — | US | claimed |
| WO-2013050938-A1 | 3,7-DIAZABICYCLO[3.3.1]NONANE AND 9-OXA-3,7-DIAZABICYCLO[3.3.1]NONANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2013-04-11 | — | — | WO | claimed |
| WO-2012085852-A1 | 3,8-DIAZA-BICYCLO[4.2.0]OCT-8-YL AMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-06-28 | — | — | WO | claimed |
| WO-2012085857-A1 | 3,8-DIAZA-BICYCLO[4.2.0]OCT-3-YL AMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-06-28 | — | — | WO | claimed |
| CN-1688547-A | A-'7-halo-2-quino (xa-) linyloxy!phenoxy-propionic acid derivatives as antineoplastic agents | UNIV WAYNE STATE (US) | 2005-10-26 | — | — | CN | claimed |
| EP-0268554-B1 | 1,5-DIPHENYL PYRAZOLE-3-CARBONIC-ACID DERIVATIVES FOR THE PROTECTION OF CULTURED PLANTS | CIBA-GEIGY AG (CH) | 1991-12-27 | — | — | EP | claimed |
| EP-2389066-B1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LTD (GB) | 2017-07-05 | — | — | EP | disclosed |
| EP-2387569-B1 | HERBCIDES | SYNGENTA LTD (GB) | 2016-06-15 | — | — | EP | disclosed |
| US-9102642-B2 | Herbicidally active cyclic diones and derivatives thereof, processes for their preparation, compositions, and methods of controlling weeds | SYNGENTA LIMITED (GB) | 2015-08-11 | — | — | US | disclosed |
| EP-2393796-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2015-02-25 | — | — | EP | disclosed |
| US-20140378305-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2014-12-25 | — | — | US | disclosed |
| WO-2008107398-A2 | PYRAZINE COMPOUNDS | BASF SE (DE) | 2008-09-12 | — | — | WO | disclosed |
| CN-101155577-A | Local treatment of neurofibromas | NEXGENIX PHARMACEUTICALS L L C (US) | 2008-04-02 | — | — | CN | disclosed |
| CN-101011349-A | Slow release injection containing mtrosourea medicament and topoisomerase inhibitor | JINAN SHUAIHUA PHARM TECHNOLOG (CN) | 2007-08-08 | — | — | CN | disclosed |
| CN-101011341-A | Slow release injection containing anti-metabolism medicament and topoisomerase inhibitor | JINAN KANGQUAN PHARM TECHNOLOG (CN) | 2007-08-08 | — | — | CN | disclosed |
| CN-1824319-A | Hormone kind anticancer medicine slow release agent | JINAN KANGQUAN MEDICINE SCI & (CN) | 2006-08-30 | — | — | CN | disclosed |
| CN-1688547-A | A-'7-halo-2-quino (xa-) linyloxy!phenoxy-propionic acid derivatives as antineoplastic agents | UNIV WAYNE STATE (US) | 2005-10-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378305-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | F7 4680/4885F3 4491/4885DYRK1A 943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.