SCHEMBL405980

SCHEMBL405980

Clc1ccc2n[c]cnc2c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 1/20 0.42
F3 P13726 1/20 0.42
DYRK1A Q13627 1/20 0.42
NR4A2 P43354 3/20 0.38
PIK3CG P48736 1/20 0.37
SOS2 Q07890 1/20 0.36
HRH4 Q9H3N8 2/20 0.35
ALDH1A1 P00352 4/20 0.34
PARP1 P09874 1/20 0.34
RAB9A P51151 2/20 0.34
NPC1 O15118 1/20 0.34
MAPT P10636 2/20 0.33
KDM4E B2RXH2 2/20 0.33
HSD17B10 Q99714 2/20 0.33
GLA P06280 2/20 0.33
HPGD P15428 2/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
KMT2A Q03164 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL404365 0.92 F7 (0.42) F7F3DYRK1ANR4A2PIK3CG
SCHEMBL4742084 0.76 MAPK13 (0.37) DYRK1A
SCHEMBL435814 0.75 KDM4E (0.38) ALDH1A1PARP1RAB9ANPC1MAPT
SCHEMBL2300942 0.75 NQO2 (0.42) ALDH1A1PARP1RAB9ANPC1MAPT
SCHEMBL7040872 0.72 ALDH1A1 (0.48) ALDH1A1RAB9ANPC1MAPTKDM4E
SCHEMBL407903 0.71 KDM4E (0.43) DYRK1APARP1KDM4E
SCHEMBL2306818 0.71 SCN10A (0.36) ALDH1A1RAB9AMAPTKDM4EHSD17B10
SCHEMBL780179 0.70 NR4A2 (0.56) F7F3DYRK1ANR4A2PIK3CG
Bromide SCHEMBL11411808 0.69 NR4A2 (0.54) F7F3DYRK1ANR4A2PIK3CG
SCHEMBL2511032 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118164921-A Propyl phenoxypropionate compound, preparation method thereof and application thereof as herbicide 山东德瑞克化工科技有限公司 2024-06-11 CN claimed
EP-2389066-B1 CYCLOPENTADIONE DERIVED HERBICIDES SYNGENTA LTD (GB) 2017-07-05 EP claimed
EP-2387569-B1 HERBCIDES SYNGENTA LTD (GB) 2016-06-15 EP claimed
US-8895474-B2 Herbicidally active cyclopentanediones and derivatives thereof, and their use in controlling weeds SYNGENTA LIMITED (GB) 2014-11-25 US claimed
US-8865623-B2 Herbicidally active cyclic diones and derivatives thereof, processes for their preparation, compositions, and method of controlling weeds SYNGENTA LIMITED (GB) 2014-10-21 US claimed
WO-2013050938-A1 3,7-DIAZABICYCLO[3.3.1]NONANE AND 9-OXA-3,7-DIAZABICYCLO[3.3.1]NONANE DERIVATIVES ACTELION PHARMACEUTICALS LTD (CH) 2013-04-11 WO claimed
WO-2012085852-A1 3,8-DIAZA-BICYCLO[4.2.0]OCT-8-YL AMIDES ACTELION PHARMACEUTICALS LTD (CH) 2012-06-28 WO claimed
WO-2012085857-A1 3,8-DIAZA-BICYCLO[4.2.0]OCT-3-YL AMIDES ACTELION PHARMACEUTICALS LTD (CH) 2012-06-28 WO claimed
CN-1070641-A Quinoxalinyl oxygen ether with the mutual resistance weeding of relevant application DU PONT (US) 1993-04-07 CN claimed
EP-0148119-B1 AMIDES OF 2-PHENOXYPROPIONIC ACID CIBA-GEIGY AG (CH) 1989-05-03 EP claimed
US-4640703-A CONTROLLING GRASSES IN CROPS CIBA-GEIGY CORPORATION (US) 1987-02-03 US claimed
CN-86103114-A The halogenated alkoxy benzene of 2-(4-heterocyclic oxy group phenoxy group) alkanoic acid is for the preparation of amide derivatives and as herbicide applications 1986-12-17 CN claimed
EP-0148119-A2 Amides of 2-phenoxypropionic acid CIBA-GEIGY AG (CH) 1985-07-10 EP claimed
CN-118164921-A Propyl phenoxypropionate compound, preparation method thereof and application thereof as herbicide 山东德瑞克化工科技有限公司 2024-06-11 CN disclosed
WO-2023131947-A1 PROCESS FOR THE PREPARATION OF ARYLOXYPHENOXYPROPIONIC ACID DERIVATIVES IN A NON POLAR SOLVENT WITH A TERTIARY AMINE CATALYST ADAMA AGAN LTD. (IL) 2023-07-13 WO disclosed
EP-4209486-A1 PROCESS FOR THE PREPARATION OF ARYLOXYPHENOXYPROPIONIC ACID DERIVATIVES IN A NON POLAR SOLVENT WITH A TERTIARY AMINE CATALYST Adama Agan Ltd. (IL) 2023-07-12 EP disclosed
US-4640703-A CONTROLLING GRASSES IN CROPS CIBA-GEIGY CORPORATION (US) 1987-02-03 US disclosed
CN-86103114-A The halogenated alkoxy benzene of 2-(4-heterocyclic oxy group phenoxy group) alkanoic acid is for the preparation of amide derivatives and as herbicide applications 1986-12-17 CN disclosed
US-4601748-A 2-phenoxy propionic acid derivatives of pentite, process for the production of these compounds as well as compositions containing the same having herbicidal effectiveness SCHERING AKTIENGESELLSCHAFT (DE) 1986-07-22 US disclosed
EP-0148119-A2 Amides of 2-phenoxypropionic acid CIBA-GEIGY AG (CH) 1985-07-10 EP disclosed