SCHEMBL780179

SCHEMBL780179

Clc1ccc2nccnc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 4/20 0.56
SOS2 Q07890 1/20 0.52
F7 P08709 1/20 0.50
F3 P13726 1/20 0.50
DYRK1A Q13627 1/20 0.50
HTT P42858 1/20 0.49
NPC1 O15118 4/20 0.47
RAB9A P51151 4/20 0.47
KMT2A Q03164 3/20 0.47
MEN1 O00255 1/20 0.47
POLB P06746 1/20 0.47
CYP1A2 P05177 1/20 0.46
PIK3CG P48736 1/20 0.43
MAPT P10636 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CCR1 P32246 1/20 0.43
PKM P14618 1/20 0.43
ALOX15 P16050 1/20 0.43
CASP1 P29466 1/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27879386 0.97 NR4A2 (0.54) NR4A2SOS2F7F3DYRK1A
Bromide SCHEMBL11411808 0.97 NR4A2 (0.54) NR4A2SOS2F7F3DYRK1A
SCHEMBL14919991 0.75 PIM1 (0.50) HTTNPC1RAB9AKMT2AMEN1
SCHEMBL9257557 0.73 HRH4 (0.47) NR4A2F7F3DYRK1AHTT
SCHEMBL5157381 0.72 PIK3CG (0.58) NR4A2F7F3DYRK1AKMT2A
SCHEMBL8337311 0.72 NPC1 (0.52) DYRK1ANPC1RAB9AKMT2AMEN1
SCHEMBL31061987 0.72 NR4A2 (0.53) NR4A2SOS2HTTNPC1RAB9A
SCHEMBL8401811 0.72 PIK3CG (0.47) NR4A2SOS2F7F3DYRK1A
SCHEMBL29393522 0.72 NR4A2 (1.00) NR4A2SOS2HTTNPC1RAB9A
SCHEMBL317870 0.72 NR4A2 (1.00) NR4A2SOS2HTTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4168401-B1 SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2026-01-07 EP claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
US-20230227429-A1 SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2023-07-20 US claimed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US claimed
CN-104513234-A Synthesis method for high-quality quizalofop-P-tefuryl JIANGSU TIANRONG GROUP CO LTD 2015-04-15 CN claimed
CN-102584803-A Preparation method of high-content quizalofop-P-tefuryl Jiangsu fengshan group co ltd 2012-07-18 CN claimed
CN-121931199-A Method for synthesizing quinoxaline and derivative thereof by using chemical enzyme synergistic catalytic system 南京工业大学 2026-04-28 CN disclosed
CN-119822910-A Method for catalyzing heterogeneous reduction of nitrogen-containing heterocyclic compound by using magnesium metal 延安大学 2025-04-15 CN disclosed
CN-118546099-A Production method of low-sulfur impurity 2, 6-dichloro quinoxaline 濮阳市旌胜新能源科技有限公司 2024-08-27 CN disclosed
CN-118027042-A Organic electroluminescent compound and organic electroluminescent device comprising the same 罗门哈斯电子材料韩国有限公司 2024-05-14 CN disclosed
CN-111094508-B Organic electroluminescent compound and organic electroluminescent device comprising the same 罗门哈斯电子材料韩国有限公司 2024-03-08 CN disclosed
CN-117143018-A Synthesis method of rare earth catalytic nitrogen-containing heterocyclic compound 温州大学新材料与产业技术研究院 2023-12-01 CN disclosed
CN-1017994-B Process for producing 2-quinoxalinol UNIROYAL CHEM CO INC (US) 1992-08-26 CN disclosed
CN-1060008-A The 4-Quinoxalinyloxy pheroxyalkylnitrile herbicides UNIROYAL CHEM CO INC (US) 1992-04-08 CN disclosed
CN-1035505-A Heterocyclic-alkylene quinoxalinyloxyphenoherbicideste herbicideste UNIROYAL CHEM CO INC (US) 1989-09-13 CN disclosed
CN-1030915-A The process for selective reduction of 2-quinoxaline-4-oxide compound UNIROYAL CHEM CO INC (US) 1989-02-08 CN disclosed
CN-1030914-A The production method of 2-quinoxaline UNIROYAL CHEM CO INC (US) 1989-02-08 CN disclosed
CN-87103559-A Macrolide compounds, their production and use 1988-01-27 CN disclosed
EP-0042750-A2 Quinoxalinyloxy ethers as selective weed control agents E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-12-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227429-A1 SULPHONAMIDE COMPOUNDS MLKL, RIPK3, CASP1 NR4A2 4383/4885SOS2 599/4885F7 3770/4885
US-10224485-B2 Process for preparing a crystalline organic semiconductor material STOM, SPOP, TTR NR4A2 3035/4885SOS2 18/4885F7 3829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.