Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.37 |
| ▸ | CTSL | P07711 | 4/20 | 0.37 |
| ▸ | CTSS | P25774 | 4/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041785 | 0.93 | PREP (0.35) | CTSKCTSLCTSS | |
| SCHEMBL4047693 | 0.92 | CTSK (0.40) | CTSKCTSLCTSS | |
| SCHEMBL4047540 | 0.90 | CTSK (0.47) | CTSKCTSLCTSS | |
| SCHEMBL4050085 | 0.89 | CTSS (0.40) | CTSKCTSLCTSS | |
| SCHEMBL4037824 | 0.88 | CTSK (0.36) | CTSKCTSLCTSSELANE | |
| SCHEMBL4050717 | 0.88 | CTSK (0.44) | CTSKCTSLCTSSELANE | |
| SCHEMBL4049692 | 0.88 | CTSK (0.37) | CTSKCTSLCTSSELANE | |
| SCHEMBL4047790 | 0.87 | CTSK (0.36) | CTSKCTSLCTSSELANE | |
| SCHEMBL4046569 | 0.84 | CTSK (0.35) | CTSKCTSLCTSSELANE | |
| SCHEMBL4040745 | 0.83 | HSD17B10 (0.36) | CTSKCTSLCTSSELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732917-B8 | SELECTED CGRP ANTAGONISTS, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INT (DE) | 2009-09-09 | — | — | EP | disclosed |
| EP-1463728-B1 | FUSED CYCLIC MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | BRISTOL MYERS SQUIBB CO (US) | 2009-01-14 | — | — | EP | disclosed |
| EP-1732917-A1 | SELECTED CGRP ANTAGONISTS, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005092880-A1 | SELECTED CGRP ANTAGONISTS, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-10-06 | — | — | WO | disclosed |