Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | KCNB1 | Q14721 | 7/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034103 | 0.81 | SMPD3 (0.40) | PTGDR2HDAC2SMPD3CHEK2ERN1 | |
| SCHEMBL4039376 | 0.79 | PTGDR2 (0.40) | PTGDR2HDAC2SMPD3CHEK2ERN1 | |
| SCHEMBL15225671 | 0.73 | SMPD3 (0.40) | PTGDR2HDAC2SMPD3CHEK2ERN1 | |
| SCHEMBL4034089 | 0.72 | SMPD3 (0.46) | PTGDR2SMPD3ERN1MAPT | |
| SCHEMBL1307966 | 0.72 | HDAC2 (0.47) | PTGDR2HDAC2SMPD3CHEK2EGFR | |
| SCHEMBL15226001 | 0.71 | SMPD3 (0.40) | PTGDR2HDAC2SMPD3CHEK2 | |
| SCHEMBL4036742 | 0.71 | SMPD3 (0.38) | PTGDR2HDAC2SMPD3CHEK2ERN1 | |
| SCHEMBL27409981 | 0.71 | POLB (0.50) | PTGDR2HDAC2SMPD3EGFRKCNB1 | |
| SCHEMBL4035391 | 0.70 | PTGDR2 (0.40) | PTGDR2SMPD3CHEK2ERN1KCNB1 | |
| SCHEMBL4034301 | 0.68 | GABRA1 (0.41) | PTGDR2SMPD3ERN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066632-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | Chong Kun Dang Pharmaceutical Corp. (KR) | 2009-06-10 | — | — | EP | claimed |
| WO-2008038955-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2008-04-03 | — | — | WO | claimed |