Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.36 |
| ▸ | TUBB | P07437 | 2/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4042546 | 0.92 | MAPT (0.43) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL4039716 | 0.89 | ERN1 (0.43) | MAPTSMPD3PTGDR2ERN1TUBB1 | |
| SCHEMBL4042076 | 0.88 | MAPT (0.39) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL4034089 | 0.87 | SMPD3 (0.46) | MAPTSMPD3PTGDR2ERN1TUBB1 | |
| SCHEMBL15225671 | 0.86 | SMPD3 (0.40) | MAPTSMPD3PTGDR2ERN1TUBB1 | |
| SCHEMBL4034103 | 0.86 | SMPD3 (0.40) | MAPTSMPD3PTGDR2ERN1TUBB1 | |
| SCHEMBL4040171 | 0.86 | TUBB4A (0.41) | MAPTSMPD3PTGDR2ALDH1A1ERN1 | |
| SCHEMBL4039129 | 0.83 | IMPDH2 (0.38) | MAPTSMPD3 | |
| SCHEMBL4035391 | 0.82 | PTGDR2 (0.40) | MAPTSMPD3PTGDR2ERN1TUBB1 | |
| SCHEMBL4036344 | 0.81 | SMPD3 (0.41) | MAPTSMPD3PTGDR2ERN1TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066632-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | Chong Kun Dang Pharmaceutical Corp. (KR) | 2009-06-10 | — | — | EP | claimed |
| WO-2008038955-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2008-04-03 | — | — | WO | claimed |