⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL355253 | 0.86 | GAA (0.55) | — | |
| SCHEMBL18048520 | 0.81 | — | — | |
| SCHEMBL11031342 | 0.80 | — | — | |
| SCHEMBL11651480 | 0.79 | LMNA (0.48) | — | |
| SCHEMBL28604705 | 0.79 | LMNA (0.48) | — | |
| SCHEMBL154280 | 0.79 | GAA (0.53) | — | |
| SCHEMBL9825086 | 0.78 | LMNA (0.44) | — | |
| SCHEMBL42229 | 0.78 | — | — | |
| SCHEMBL8944774 | 0.77 | ALDH1A1 (0.50) | — | |
| SCHEMBL250456 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889154-A1 | HETEROCYCLIC COMPOUND INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Wuhan LL Science And Technology Development Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |
| WO-2021028806-A1 | HETEROCYCLIC WDR5 INHIBITORS AS ANTI-CANCER COMPOUNDS | NOVARTIS AG (CH) | 2021-02-18 | — | — | WO | disclosed |
| WO-2021026672-A1 | HETEROCYCLIC WDR5 INHIBITORS AS ANTI-CANCER COMPOUNDS | NOVARTIS AG (CH) | 2021-02-18 | — | — | WO | disclosed |
| WO-2020157652-A2 | CDK2 INHIBITORS | PFIZER INC. (US) | 2020-08-06 | — | — | WO | disclosed |
| WO-2019014315-A1 | RAD51 INHIBITORS | CYTEIR THERAPEUTICS, INC. (US) | 2019-01-17 | — | — | WO | disclosed |
| US-9847229-B2 | Method for forming a semiconductor device and semiconductor device | INFINEON TECHNOLOGIES AG (DE) | 2017-12-19 | — | — | US | disclosed |
| US-9526648-B2 | Intragastric device for treating obesity | SYNERZ MEDICAL, INC. (US) | 2016-12-27 | — | — | US | disclosed |
| US-20160287114-A1 | NEUROMODULATION SYSTEMS HAVING NERVE MONITORING ASSEMBLIES AND ASSOCIATED DEVICES, SYSTEMS, AND METHODS | MEDTRONIC ARDIAN LUXEMBOURG S.A.R.L. (LU) | 2016-10-06 | — | — | US | disclosed |
| CN-102695545-B | Compositions comprising enzymatically cleavable ketone-modified opioid prodrugs and optional inhibitors thereof | 特色疗法股份有限公司 | 2016-08-17 | — | — | CN | disclosed |
| US-20160163177-A1 | Water Use/Water Energy Use Monitor and/or Leak Detection System | KLICPERA MICHAEL EDWARD (US) | 2016-06-09 | — | — | US | disclosed |
| US-6200935-B1 | FOR CONTROLLING UNDESIRABLE PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-03-13 | — | — | US | disclosed |
| US-6162765-A | Substituted N-aryl nitrogen-containing heterocyclic compounds | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-19 | — | — | US | disclosed |
| EP-1051414-A1 | SUBSTITUTED HETEROARYLMETHYL COMPOUNDS USED AS HERBICIDES | Bayer Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999038861-A1 | SUBSTITUTED HETEROARYLMETHYL COMPOUNDS USED AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-08-05 | — | — | WO | disclosed |
| EP-0797573-A1 | 3-ARYL-1,2,4-TRIAZOLE DERIVATIVES WITH HERBICIDAL PROPERTIES | BAYER AG (DE) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996018618-A1 | 3-ARYL-1,2,4-TRIAZOLE DERIVATIVES WITH HERBICIDAL PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-20 | — | — | WO | disclosed |
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |
| EP-0553594-A1 | Polymeric thermoplastic materials, comprising 1,2,4-triazolidine-3,5-dione derivatives as stabilisers | CIBA-GEIGY AG (CH) | 1993-08-04 | — | — | EP | disclosed |
| US-5196465-A | Heat resistance | CIBA-GEIGY CORPORATION (US) | 1993-03-23 | — | — | US | disclosed |
| US-4076938-A | Process for the production of 3-hydroxy-1,2,4-triazole derivatives | CIBA-GEIGY CORPORATION (US) | 1978-02-28 | — | — | US | disclosed |