Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 9/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 9/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3300820 | 0.84 | PDE3B (0.42) | FFAR1L3MBTL1CYP4F2CYP4A11PDE3B | |
| SCHEMBL27774507 | 0.81 | ALDH1A1 (0.49) | LMNA | |
| SCHEMBL12924822 | 0.80 | FFAR1 (0.53) | FFAR1L3MBTL1LMNAFFAR4 | |
| SCHEMBL28904650 | 0.77 | MAPT (0.51) | L3MBTL1PDE3BPDE3AP2RY12 | |
| SCHEMBL30026033 | 0.77 | MAPT (0.51) | L3MBTL1PDE3BPDE3AP2RY12 | |
| SCHEMBL12896079 | 0.77 | FFAR1 (0.49) | FFAR1L3MBTL1LMNAFFAR4 | |
| SCHEMBL3306252 | 0.76 | PDE3B (0.43) | L3MBTL1LMNAPDE3BPDE3AP2RY12 | |
| SCHEMBL3306255 | 0.76 | PDE3B (0.43) | L3MBTL1LMNAPDE3BPDE3AP2RY12 | |
| SCHEMBL10030181 | 0.76 | L3MBTL1 (0.55) | L3MBTL1LMNAPDE3BPDE3AP2RY12 | |
| SCHEMBL2053753 | 0.75 | FFAR1 (0.67) | FFAR1FFAR4CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066637-A1 | NOVEL SUBSTITUTED BIPYRIDINE DERIVATIVES AND THEIR USE AS ADENOSINE RECEPTOR LIGANDS | Bayer HealthCare AG (DE) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008028590-A1 | NOVEL SUBSTITUTED BIPYRIDINE DERIVATIVES AND THEIR USE AS ADENOSINE RECEPTOR LIGANDS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | disclosed |