Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 11/20 | 0.72 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2202554 | 0.85 | EGLN1 (0.80) | EGLN1RAB9AKMT2AMEN1NPC1 | |
| SCHEMBL4047637 | 0.84 | EGLN1 (0.83) | EGLN1RAB9APOLBKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7693361 | 0.84 | EGLN1 (0.79) | EGLN1RAB9AKMT2AMEN1NPC1 | |
| SCHEMBL4039311 | 0.82 | EGLN1 (0.74) | EGLN1LMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7691643 | 0.82 | EGLN1 (0.76) | EGLN1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL4038377 | 0.81 | MEN1 (0.69) | EGLN1RAB9AKMT2AMEN1GAA | |
| SCHEMBL7687778 | 0.80 | EGLN1 (0.73) | EGLN1RAB9AKMT2AMEN1NPC1 | |
| SCHEMBL7969151 | 0.80 | EGLN1 (0.69) | EGLN1RAB9ANPC1MAPT | |
| SCHEMBL7962193 | 0.80 | EGLN1 (0.72) | EGLN1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL7689878 | 0.79 | EGLN1 (0.67) | EGLN1RAB9AKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079699-A1 | QUINOLINE DERIVATIVES | Envivo Pharmaceuticals, Inc. (US) | 2009-07-22 | — | — | EP | claimed |
| WO-2008014602-A1 | QUINOLINE DERIVATIVES | ENVIVO PHARMACEUTICALS, INC. (US) | 2008-02-07 | — | — | WO | claimed |
| EP-2079699-A1 | QUINOLINE DERIVATIVES | Envivo Pharmaceuticals, Inc. (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008014602-A1 | QUINOLINE DERIVATIVES | ENVIVO PHARMACEUTICALS, INC. (US) | 2008-02-07 | — | — | WO | disclosed |