Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052357 | 0.89 | CTSK (0.32) | CTSK | |
| SCHEMBL4043974 | 0.87 | CTSK (0.33) | CTSK | |
| SCHEMBL4044092 | 0.82 | CTSK (0.35) | CTSK | |
| SCHEMBL4042191 | 0.82 | CTSK (0.36) | CTSK | |
| SCHEMBL4045574 | 0.81 | CTSK (0.33) | CTSK | |
| SCHEMBL4046902 | 0.81 | CTSK (0.33) | CTSK | |
| SCHEMBL4052224 | 0.81 | CTSK (0.33) | CTSK | |
| SCHEMBL4045017 | 0.81 | CTSK (0.33) | CTSK | |
| SCHEMBL4043885 | 0.80 | FAP (0.37) | CTSK | |
| SCHEMBL4044210 | 0.80 | CTSK (0.32) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |