Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041651 | 0.94 | CTSK (0.55) | CTSKCTSSCTSLPOLBSMYD3 | |
| SCHEMBL4047452 | 0.92 | CTSK (0.54) | CTSKCTSSCTSL | |
| SCHEMBL4043531 | 0.92 | CTSK (0.62) | CTSKCTSSCTSL | |
| SCHEMBL4042463 | 0.89 | CTSK (0.57) | CTSKCTSSCDK4CCNA2CCND1 | |
| SCHEMBL4050121 | 0.89 | CTSK (0.54) | CTSKCTSSCDK4CCNA2CCND1 | |
| SCHEMBL4047157 | 0.88 | CTSK (0.51) | CTSKCTSSCDK4CCNA2CCND1 | |
| SCHEMBL4043121 | 0.87 | CTSK (0.56) | CTSKCTSSCTSLPOLB | |
| SCHEMBL4050211 | 0.87 | CTSK (0.69) | CTSKCTSSCTSLPOLB | |
| SCHEMBL4045325 | 0.86 | CTSK (0.69) | CTSKCTSSCTSLCTSBPOLB | |
| SCHEMBL4045482 | 0.86 | CTSK (0.54) | CTSKCTSSCDK4CCNA2CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |