Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.51 |
| ▸ | CTSS | P25774 | 4/20 | 0.40 |
| ▸ | CTSL | P07711 | 3/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044918 | 0.92 | CTSK (0.62) | CTSKCTSSCTSL | |
| SCHEMBL4045586 | 0.92 | CTSK (0.54) | CTSKCTSSCTSL | |
| SCHEMBL4045482 | 0.90 | CTSK (0.54) | CTSKCTSSCTSLCTSBCDK4 | |
| SCHEMBL4038951 | 0.88 | CTSK (0.57) | CTSKCTSSCTSLCTSBCDK4 | |
| SCHEMBL4044791 | 0.88 | CTSK (0.52) | CTSKCTSSCTSLCTSBCDK4 | |
| SCHEMBL4040886 | 0.87 | CTSK (0.54) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4046497 | 0.87 | CTSK (0.66) | CTSKCTSSCTSL | |
| SCHEMBL4042169 | 0.86 | CTSK (0.67) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4050121 | 0.86 | CTSK (0.54) | CTSKCTSSCTSLCTSBCDK4 | |
| SCHEMBL4045558 | 0.85 | CTSK (0.56) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |