Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.58 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4045325 | 0.92 | CTSK (0.69) | CTSKCTSSPOLBCCR1CTSV | |
| SCHEMBL4043041 | 0.89 | CTSK (0.64) | CTSKCTSSPOLBCCR1TAS1R3 | |
| SCHEMBL4043121 | 0.89 | CTSK (0.56) | CTSKCTSSPOLBCCR1CTSV | |
| SCHEMBL4045496 | 0.89 | CTSK (0.60) | CTSKCTSSCCR1CTSVCTSL | |
| SCHEMBL4050211 | 0.88 | CTSK (0.69) | CTSKCTSSPOLBCCR1TAS1R3 | |
| SCHEMBL4045558 | 0.88 | CTSK (0.56) | CTSKCTSSPOLBCCR1CTSL | |
| SCHEMBL4041651 | 0.87 | CTSK (0.55) | CTSKCTSSPOLBCCR1CTSV | |
| SCHEMBL4045165 | 0.86 | CTSK (0.61) | CTSKCTSSCCR1CTSVCTSL | |
| SCHEMBL4047452 | 0.85 | CTSK (0.54) | CTSKCTSSCTSVCTSL | |
| SCHEMBL4043531 | 0.85 | CTSK (0.62) | CTSKCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |