Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.60 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.38 |
| ▸ | CTSV | O60911 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044579 | 0.92 | CTSK (0.71) | CTSKCTSSCCR1CACNA1BCTSV | |
| SCHEMBL4046427 | 0.89 | CTSK (0.58) | CTSKCTSSCCR1CACNA1BCTSV | |
| SCHEMBL4048924 | 0.89 | CTSK (0.68) | CTSKCTSSCCR1CACNA1BCTSV | |
| SCHEMBL4045165 | 0.89 | CTSK (0.61) | CTSKCTSSCCR1CACNA1BCTSV | |
| SCHEMBL4046824 | 0.89 | CTSK (0.70) | CTSKCTSSCCR1CTSVCTSL | |
| SCHEMBL4044908 | 0.89 | CTSK (0.58) | CTSKCTSSCCR1CTSVCTSL | |
| SCHEMBL4040326 | 0.88 | CTSK (0.56) | CTSKCTSSCCR1CACNA1BCTSV | |
| SCHEMBL4047026 | 0.86 | CTSK (0.60) | CTSKCTSSCTSL | |
| SCHEMBL4043683 | 0.86 | CTSK (0.54) | CTSKCTSSCCR1CTSVCTSL | |
| SCHEMBL4045558 | 0.85 | CTSK (0.56) | CTSKCTSSCCR1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |