SCHEMBL404591

SCHEMBL404591

NC(=O)/C=C/C=C/c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 3/20 0.63
HDAC4 P56524 3/20 0.63
HDAC1 Q13547 3/20 0.63
HDAC2 Q92769 3/20 0.63
HDAC8 Q9BY41 3/20 0.63
HDAC6 Q9UBN7 3/20 0.63
HDAC7 Q8WUI4 2/20 0.63
HDAC10 Q969S8 2/20 0.63
HDAC11 Q96DB2 2/20 0.63
HDAC9 Q9UKV0 2/20 0.63
HDAC5 Q9UQL6 2/20 0.63
MAOB P27338 8/20 0.58
ALDH1A1 P00352 3/20 0.54
MAPT P10636 3/20 0.54
LMNA P02545 3/20 0.54
CYP1A2 P05177 2/20 0.54
CYP2D6 P10635 2/20 0.54
PLIN1 O60240 2/20 0.54
RECQL P46063 2/20 0.54
PLIN5 Q00G26 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL404592 1.00 HDAC3 (0.63) HDAC3HDAC4HDAC1HDAC2HDAC8
Maleic Acid SCHEMBL28010782 0.94 HDAC3 (0.59) HDAC3HDAC4HDAC1HDAC2HDAC8
Butadiene SCHEMBL6735917 0.93 HDAC3 (0.56) HDAC3HDAC4HDAC1HDAC2HDAC8
Acrylic Acid SCHEMBL27861204 0.91 HDAC3 (0.54) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL13067862 0.89 HDAC2 (0.54) HDAC3HDAC4HDAC1HDAC2HDAC8
Methacrylic Acid SCHEMBL10791017 0.88 HDAC3 (0.51) HDAC3HDAC4HDAC1HDAC2HDAC8
Acrylonitrile SCHEMBL5153154 0.87 MCL1 (0.51) HDAC3HDAC4HDAC1HDAC2HDAC8
Maleic Anhydride SCHEMBL27994783 0.87 HDAC3 (0.50) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL11411205 0.87 HDAC3 (0.50) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL28990093 0.86 HDAC3 (0.63) HDAC3HDAC4HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160161475-A1 HYBRID SEMICONDUCTING POLYMER NANOPARTICLES AS POLARIZATION-SENSITIVE FLUORESCENT PROBES UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION 2016-06-09 US claimed
EP-3019443-A1 HYBRID SEMICONDUCTING POLYMER NANOPARTICLES AS POLARIZATION SENSITIVE FLUORESCENT PROBES University Of Washington Through Its Center For Commercialization (US) 2016-05-18 EP claimed
US-20160018405-A1 METHODS AND SYSTEMS FOR ANALYSIS USING POLYMER DOTS University of Washington Through it's Center for Commercialization (US) 2016-01-21 US claimed
US-20120161101-A1 WATER STABLE III-V SEMICONDUCTOR NANOCRYSTAL COMPLEXES AND METHODS OF MAKING SAME SAMSUNG ELECTRONICS CO., LTD (KR) 2012-06-28 US claimed
US-6872450-B2 Water-stable photoluminescent semiconductor nanocrystal complexes and method of making same EVIDENT TECHNOLOGIES (US) 2005-03-29 US claimed
US-20040115817-A1 Water-stable photoluminescent semiconductor nanocrystal complexes and method of making same EVIDENT TECHNOLOGIES, INC. 2004-06-17 US claimed
EP-3019443-B1 HYBRID SEMICONDUCTING POLYMER NANOPARTICLES AS POLARIZATION SENSITIVE FLUORESCENT PROBES UNIV WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2026-02-25 EP disclosed
US-20260014561-A1 METHODS AND APPARATUS FOR SINGLE BIOLOGICAL NANOPARTICLE ANALYSIS UNIV WASHINGTON (US) 2026-01-15 US disclosed
US-12447469-B2 Methods and apparatus for single biological nanoparticle analysis UNIVERSITY OF WASHINGTON (US) 2025-10-21 US disclosed
US-20250290930-A1 FUNCTIONALIZED CHROMOPHORIC POLYMER DOTS AND BIOCONJUGATES THEREOF CLEMSON UNIVERSITY RESEARCH FOUNDATION 2025-09-18 US disclosed
EP-3483610-B1 FUNCTIONALIZED CHROMOPHORIC POLYMER DOTS AND BIOCONJUGATES THEREOF UNIV OF WASHINGTON CENTER FOR COMMERCIALIZATION (US) 2025-09-10 EP disclosed
US-12352754-B2 Functionalized chromophoric polymer dots and bioconjugates thereof UNIVERSITY OF WASHINGTON (US) 2025-07-08 US disclosed
CN-112105912-B Method and apparatus for single biological nanoparticle analysis 华盛顿大学 2025-05-23 CN disclosed
US-20050136258-A1 Nanoparticle fluorescent probes comprised of quantum dot and hydrophobic protection structure including capping ligand and amphiphilic copolymer; biocompatibility; multiplexed imaging and detection of genes and proteins in single living cells; cancer diagnosis NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-06-23 US disclosed
US-6872450-B2 Water-stable photoluminescent semiconductor nanocrystal complexes and method of making same EVIDENT TECHNOLOGIES (US) 2005-03-29 US disclosed
EP-1493015-A1 ANALYTE SENSOR Powerzyme, Inc. (US) 2005-01-05 EP disclosed
US-20040115817-A1 Water-stable photoluminescent semiconductor nanocrystal complexes and method of making same EVIDENT TECHNOLOGIES, INC. 2004-06-17 US disclosed
US-20030228681-A1 Analyte sensor POWERZYME, INC. 2003-12-11 US disclosed
WO-2003087783-A1 ANALYTE SENSOR POWERZYME, INC. (US) 2003-10-23 WO disclosed
WO-1997000249-A1 HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-01-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014561-A1 METHODS AND APPARATUS FOR SINGLE BIOLOGICAL NANOPARTICLE ANALYSIS CD63, SELL, LAMP2 HDAC3 2808/4885HDAC4 4325/4885HDAC1 3391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.