Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 5/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL404592 | 0.89 | HDAC3 (0.63) | HDAC2HDAC6HDAC1HDAC8HDAC3 | |
| SCHEMBL404591 | 0.89 | HDAC3 (0.63) | HDAC2HDAC6HDAC1HDAC8HDAC3 | |
| SCHEMBL2455358 | 0.87 | HDAC2 (0.65) | HDAC2HDAC6HDAC1HDAC8HDAC3 | |
| SCHEMBL2455356 | 0.87 | HDAC2 (0.65) | HDAC2HDAC6HDAC1HDAC8HDAC3 | |
| SCHEMBL1232945 | 0.85 | HDAC2 (0.58) | HDAC2HDAC6HDAC1HDAC8HDAC3 | |
| SCHEMBL1232946 | 0.85 | HDAC2 (0.58) | HDAC2HDAC6HDAC1HDAC8HDAC3 | |
| SCHEMBL27705358 | 0.85 | HDAC2 (0.58) | HDAC2HDAC6HDAC1HDAC8HDAC3 | |
| Maleic Acid SCHEMBL28010782 | 0.84 | HDAC3 (0.59) | HDAC2HDAC6HDAC1HDAC8HDAC3 | |
| Butadiene SCHEMBL6735917 | 0.82 | HDAC3 (0.56) | HDAC2HDAC6HDAC1HDAC8HDAC3 | |
| SCHEMBL13294292 | 0.81 | HDAC2 (0.80) | HDAC2HDAC6HDAC1HDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896399-B1 | BIPHENYL AND NAPHTHYL-PHENYL HYDROXAMIC ACID DERIVATIVES | SIGMA TAU IND FARMACEUTI (IT) | 2010-11-17 | — | — | EP | disclosed |