Maleic Anhydride

Maleic Anhydride

SCHEMBL27994783

NC(=O)C=CC=Cc1ccccc1.O=C1C=CC(=O)O1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 2/20 0.50
HDAC4 P56524 2/20 0.50
HDAC1 Q13547 2/20 0.50
HDAC7 Q8WUI4 2/20 0.50
HDAC2 Q92769 2/20 0.50
HDAC10 Q969S8 2/20 0.50
HDAC11 Q96DB2 2/20 0.50
HDAC8 Q9BY41 2/20 0.50
HDAC6 Q9UBN7 2/20 0.50
HDAC9 Q9UKV0 2/20 0.50
HDAC5 Q9UQL6 2/20 0.50
MAOB P27338 7/20 0.47
MAPT P10636 3/20 0.47
ALDH1A1 P00352 3/20 0.47
NPC1 O15118 1/20 0.47
POLB P06746 1/20 0.47
MAOA P21397 1/20 0.47
CYP1A2 P05177 2/20 0.43
CYP2D6 P10635 2/20 0.43
LMNA P02545 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Juarezic Acid SCHEMBL27767651 0.87 HDAC3 (0.44) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL377920 0.87 HDAC3 (0.53) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL404592 0.87 HDAC3 (0.63) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL404591 0.87 HDAC3 (0.63) HDAC3HDAC4HDAC1HDAC7HDAC2
Maleic Anhydride SCHEMBL10691759 0.85 MAOB (0.61) HDAC3HDAC4HDAC1HDAC7HDAC2
Maleic Acid SCHEMBL28010782 0.82 HDAC3 (0.59) HDAC3HDAC4HDAC1HDAC7HDAC2
Maleic Anhydride SCHEMBL28146128 0.81 HDAC3 (0.50) HDAC3HDAC4HDAC1HDAC7HDAC2
Butadiene SCHEMBL6735917 0.80 HDAC3 (0.56) HDAC3HDAC4HDAC1HDAC7HDAC2
Acrylic Acid SCHEMBL27861204 0.79 HDAC3 (0.54) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL28620644 0.77 HDAC3 (0.43) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104232050-A Compound oil-soluble viscosity reducer for reducing viscosity of thickened oil and preparation method of compound oil-soluble viscosity reducer NABAI KECHUANG BEIJING TECHNOLOGY DEV CO LTD 2014-12-24 CN claimed
CN-104232050-A Compound oil-soluble viscosity reducer for reducing viscosity of thickened oil and preparation method of compound oil-soluble viscosity reducer NABAI KECHUANG BEIJING TECHNOLOGY DEV CO LTD 2014-12-24 CN disclosed
CN-104232050-A Compound oil-soluble viscosity reducer for reducing viscosity of thickened oil and preparation method of compound oil-soluble viscosity reducer NABAI KECHUANG BEIJING TECHNOLOGY DEV CO LTD 2014-12-24 CN disclosed