Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 7/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30393652 | 0.79 | LMNA (1.00) | LMNASMN1; SMN2AKR1C3AKR1C1PLK1 | |
| SCHEMBL949716 | 0.79 | LMNA (1.00) | LMNASMN1; SMN2AKR1C3AKR1C1PLK1 | |
| SCHEMBL12748677 | 0.76 | AKR1C3 (0.54) | LMNASMN1; SMN2AKR1C3AKR1C1PLK1 | |
| SCHEMBL4047014 | 0.76 | KDM4E (0.52) | LMNASMN1; SMN2AKR1C3AKR1C1PLK1 | |
| SCHEMBL19194701 | 0.75 | LMNA (0.71) | LMNASMN1; SMN2AKR1C3AKR1C1PLK1 | |
| SCHEMBL946621 | 0.75 | LMNA (0.71) | LMNASMN1; SMN2AKR1C3AKR1C1PLK1 | |
| SCHEMBL1466938 | 0.74 | AKR1C3 (0.56) | LMNASMN1; SMN2AKR1C3AKR1C1PLK1 | |
| SCHEMBL12748681 | 0.74 | AKR1C3 (0.52) | LMNASMN1; SMN2AKR1C3AKR1C1PLK1 | |
| SCHEMBL1468084 | 0.73 | AKR1C3 (0.54) | LMNASMN1; SMN2AKR1C3AKR1C1PLK1 | |
| SCHEMBL1465894 | 0.73 | AKR1C3 (0.54) | LMNASMN1; SMN2AKR1C3AKR1C1PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101166746-B | Process for preparing substituted benzothiazinoindoles | SUVEN LIFE SCIENCES LTD | 2011-09-28 | — | — | CN | disclosed |
| EP-1856132-B1 | PROCESS FOR PREPARING SUBSTITUTED BENZOTHIAZINOINDOLES | SUVEN LIFE SCIENCES LTD (IN) | 2009-04-01 | — | — | EP | disclosed |
| US-20080119646-A1 | Process for Preparing Substituted Benzothiazinoindoles | SUVEN LIFE SCIENCES LIMITED (IN) | 2008-05-22 | — | — | US | disclosed |
| CN-101166746-A | Process for preparing substituted benzothiazinoindoles | SUVEN LIFE SCIENCES LTD (IN) | 2008-04-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119646-A1 | Process for Preparing Substituted Benzothiazinoindoles | C5, CYP8B1, CBR1 | LMNA 1605/4885SMN1; SMN2 4819/4885AKR1C3 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.