Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | ACACA | Q13085 | 2/20 | 0.38 |
| ▸ | NPC1L1 | Q9UHC9 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL772324 | 0.93 | CNR2 (0.42) | CNR2PRKCAMMP12NPC1L1CYP3A4 | |
| SCHEMBL793146 | 0.91 | CNR2 (0.40) | CNR2ACACBACACACYP3A4CYP2C19 | |
| SCHEMBL10283557 | 0.86 | CNR2 (0.37) | CNR2OPRM1OPRD1OPRK1OGFRL1 | |
| SCHEMBL771603 | 0.83 | CNR2 (0.37) | CNR2PRKCAMMP12NPC1L1CYP3A4 | |
| SCHEMBL772007 | 0.81 | CNR2 (0.40) | CNR2PRKCAMMP12NPC1L1CYP3A4 | |
| SCHEMBL793072 | 0.80 | CNR2 (0.36) | CNR2OPRM1OPRD1OPRK1OGFRL1 | |
| SCHEMBL792727 | 0.79 | DRD2 (0.44) | CNR2OPRM1OPRD1OPRK1OGFRL1 | |
| SCHEMBL773128 | 0.77 | CNR2 (0.41) | CNR2NPC1L1CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL5307726 | 0.77 | PRKCA (0.48) | PRKCAMMP12CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL13011489 | 0.76 | CNR2 (0.57) | CNR2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1719773-B1 | FUSED HETEROTETRACYCLIC COMPOUNDS AND USE TEHREOF AS HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC (JP) | 2009-04-15 | — | — | EP | disclosed |