Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 12/20 | 0.53 |
| ▸ | KIF23 | Q02241 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4039298 | 0.95 | KIF11 (0.54) | KIF11KIF23MEN1KMT2AGAA | |
| SCHEMBL4039243 | 0.87 | KIF11 (0.53) | KIF11KIF23MEN1KMT2AGAA | |
| SCHEMBL3867071 | 0.87 | KIF11 (0.59) | KIF11KIF23GAAMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL3873756 | 0.86 | KIF11 (0.59) | KIF11KIF23GAAMAPTNPSR1 | |
| SCHEMBL5100450 | 0.83 | MEN1 (0.45) | KIF11MEN1KMT2AGAAMAPT | |
| SCHEMBL4039832 | 0.81 | KIF11 (0.48) | KIF11KIF23GAAMAPTNPSR1 | |
| SCHEMBL5100270 | 0.81 | KIF11 (0.51) | KIF11MEN1KMT2AGAAMAPT | |
| SCHEMBL3866928 | 0.81 | KIF11 (0.52) | KIF11KIF23 | |
| SCHEMBL3837879 | 0.80 | MEN1 (0.41) | KIF11MEN1KMT2AGAAMAPT | |
| SCHEMBL3838937 | 0.80 | KIF11 (0.40) | KIF11MEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601673-B1 | FUSED HETEROCYCLES AND USES THEREOF | ASTRAZENECA AB (SE) | 2009-06-10 | — | — | EP | disclosed |