Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.52 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.52 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 4/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691625 | 0.84 | KDM1A (0.40) | ALDH1A1GAAFGFR1FGFR2KDM4E | |
| SCHEMBL416493 | 0.81 | DCUN1D1 (0.54) | ALDH1A1GAAFGFR1FGFR2DCUN1D1 | |
| SCHEMBL29930881 | 0.79 | DCUN1D1 (0.49) | ALDH1A1GAAFGFR1FGFR2DCUN1D1 | |
| SCHEMBL14424580 | 0.79 | DCUN1D1 (0.49) | ALDH1A1GAAFGFR1FGFR2DCUN1D1 | |
| SCHEMBL1691623 | 0.79 | DRD1 (0.44) | ALDH1A1GAAFGFR1FGFR2KDM4E | |
| SCHEMBL15330909 | 0.77 | DCUN1D1 (0.46) | ALDH1A1GAAFGFR1FGFR2DCUN1D1 | |
| SCHEMBL22750820 | 0.77 | NPC1 (0.47) | ALDH1A1GAADCUN1D1HSP90AA1METAP2 | |
| SCHEMBL1528695 | 0.74 | CXCR2 (0.48) | ALDH1A1GAADCUN1D1KDM4EPDE5A | |
| SCHEMBL12453606 | 0.73 | POLB (0.53) | ALDH1A1GAADCUN1D1KDM4EPDE5A | |
| SCHEMBL28054336 | 0.73 | ALDH1A1 (0.44) | ALDH1A1GAADCUN1D1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730124-A4 | CERTAIN TRIAZOLE-BASED COMPOUNDS, COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORP (US) | 2009-04-01 | — | — | EP | claimed |
| EP-1730124-A1 | CERTAIN TRIAZOLE-BASED COMPOUNDS, COMPOSITIONS, AND USES THEREOF | Amphora Discovery Corporation (US) | 2006-12-13 | — | — | EP | claimed |
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | claimed |
| WO-2005097758-A1 | CERTAIN TRIAZOLE-BASED COMPOUNDS, COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-10-20 | — | — | WO | claimed |
| EP-1730124-A4 | CERTAIN TRIAZOLE-BASED COMPOUNDS, COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORP (US) | 2009-04-01 | — | — | EP | disclosed |
| EP-1730124-A1 | CERTAIN TRIAZOLE-BASED COMPOUNDS, COMPOSITIONS, AND USES THEREOF | Amphora Discovery Corporation (US) | 2006-12-13 | — | — | EP | disclosed |
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
| WO-2005097758-A1 | CERTAIN TRIAZOLE-BASED COMPOUNDS, COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | ALDH1A1 720/4885GAA 85/4885FGFR1 4538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.