SCHEMBL15330909

SCHEMBL15330909

COc1ccccc1-c1nnc(C=O)[nH]1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DCUN1D1 Q96GG9 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALDH1A1 P00352 2/20 0.45
GAA P10253 1/20 0.45
PDE5A O76074 4/20 0.44
AURKA O14965 1/20 0.44
FGFR1 P11362 1/20 0.44
FGFR2 P21802 1/20 0.44
ALPL P05186 1/20 0.43
ERN1 O75460 1/20 0.42
PARP1 P09874 1/20 0.42
ALOX15 P16050 1/20 0.42
HSD17B10 Q99714 1/20 0.42
METAP2 P50579 1/20 0.41
KDM4E B2RXH2 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL416493 0.78 DCUN1D1 (0.54) DCUN1D1L3MBTL1ALDH1A1GAAPDE5A
SCHEMBL14424580 0.77 DCUN1D1 (0.49) DCUN1D1L3MBTL1ALDH1A1GAAPDE5A
SCHEMBL29930881 0.77 DCUN1D1 (0.49) DCUN1D1L3MBTL1ALDH1A1GAAPDE5A
SCHEMBL4046314 0.77 ALDH1A1 (0.55) DCUN1D1ALDH1A1GAAPDE5AAURKA
SCHEMBL1528695 0.75 CXCR2 (0.48) DCUN1D1L3MBTL1ALDH1A1GAAPDE5A
SCHEMBL15329999 0.75 ALDH1A1 (0.45) DCUN1D1L3MBTL1ALDH1A1GAAPARP1
SCHEMBL8963941 0.74 L3MBTL1 (0.59) DCUN1D1L3MBTL1ALDH1A1GAAPDE5A
SCHEMBL15332409 0.72 DCUN1D1 (0.48) DCUN1D1L3MBTL1ALDH1A1GAAPDE5A
SCHEMBL645245 0.72 FGFR1 (0.60) DCUN1D1L3MBTL1ALDH1A1FGFR1FGFR2
SCHEMBL3394704 0.71 ALDH1A1 (0.53) DCUN1D1ALDH1A1GAAPDE5AAURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed