Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 19/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1365799 | 0.93 | HRH3 (0.53) | MCHR1HRH3CYP3A4 | |
| SCHEMBL13748840 | 0.89 | MCHR1 (0.49) | MCHR1HRH3 | |
| SCHEMBL4044960 | 0.85 | MCHR1 (0.47) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL4054734 | 0.85 | MCHR1 (0.47) | MCHR1HRH3 | |
| SCHEMBL4050690 | 0.83 | MCHR1 (0.53) | MCHR1 | |
| SCHEMBL13748119 | 0.83 | MCHR1 (0.50) | MCHR1 | |
| SCHEMBL4047406 | 0.83 | MCHR1 (0.55) | MCHR1 | |
| SCHEMBL13748855 | 0.83 | MCHR1 (0.43) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL1367249 | 0.82 | MCHR1 (0.45) | MCHR1KCNH2HRH3CYP3A4 | |
| SCHEMBL1366707 | 0.82 | MCHR1 (0.66) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103478-A1 | PYRIDONE AND PYRIDAZINONE DERIVATIVES AS MCH ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009103478-A1 | PYRIDONE AND PYRIDAZINONE DERIVATIVES AS MCH ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-27 | — | — | WO | disclosed |