SCHEMBL4046853

SCHEMBL4046853

Oc1ccc(Oc2ccccc2F)cc1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.61
LTA4H P09960 2/20 0.56
NR1H2 P55055 1/20 0.56
BAX Q07812 1/20 0.56
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
ESR1 P03372 1/20 0.52
ESR2 Q92731 1/20 0.52
LPAR1 Q92633 2/20 0.46
LPAR5 Q9H1C0 2/20 0.46
FAAH O00519 1/20 0.45
ALDH1A1 P00352 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
MAPK1 P28482 1/20 0.43
HTT P42858 1/20 0.43
LMNA P02545 1/20 0.43
CXCL8 P10145 1/20 0.43
DAO P14920 1/20 0.42
FFAR1 O14842 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6293051 0.89 PARP10 (0.66) PARP10MEN1KMT2AESR1LPAR1
SCHEMBL6289863 0.87 PARP10 (0.63) PARP10MEN1KMT2AESR1LPAR1
SCHEMBL6293904 0.85 PARP10 (0.61) PARP10MEN1KMT2AESR1LPAR1
SCHEMBL6293879 0.85 PARP10 (0.61) PARP10MEN1KMT2AESR1LPAR1
SCHEMBL2458461 0.85 PARP10 (0.61) PARP10MEN1KMT2AESR1LPAR1
SCHEMBL6290343 0.85 PARP10 (0.61) PARP10MEN1KMT2AESR1LPAR1
SCHEMBL4211500 0.84 LTA4H (0.68) PARP10LTA4HNR1H2BAXMEN1
SCHEMBL6290371 0.83 PARP10 (0.59) PARP10LTA4HMEN1KMT2AESR1
SCHEMBL6290746 0.83 PARP10 (0.59) PARP10LTA4HMEN1KMT2AESR1
SCHEMBL702582 0.82 PARP10 (0.58) PARP10LTA4HMEN1KMT2AESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017093351-A1 CPLA2 INHIBITORS Westfälische Wilhelms-Universität Münster (DE) 2017-06-08 WO disclosed
EP-1380342-B1 COMPLEX CATALYST, PROCESS FOR PRODUCING THE COMPLEX CATALYST, AND PROCESS FOR PRODUCING ALCOHOL DERIVATIVE WITH THE COMPLEX CATALYST SUMITOMO CHEMICAL CO (JP) 2009-07-01 EP disclosed
CN-1281320-C Complex catalyst process for producing the complex catalyst and process for producing alcohol derivative with the complex catalyst SUMITOMO CHEMICAL CO (JP) 2006-10-25 CN disclosed
US-6995110-B2 Complex catalyst, process for producing the complex catalyst, and process for producing alcohol derivative with the complex catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-02-07 US disclosed
CN-1503696-A Complex catalyst, process for producing the complex catalyst, and process for producing alcohol derivative using the complex catalyst ס�ѻ�ѧ��ҵ��ʽ���� 2004-06-09 CN disclosed
US-20040077487-A1 Complex catalyst, process for producing the complex catalyst, and process for producing alchohol derivative with the complex catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-04-22 US disclosed
EP-1380342-A1 COMPLEX CATALYST, PROCESS FOR PRODUCING THE COMPLEX CATALYST, AND PROCESS FOR PRODUCING ALCOHOL DERIVATIVE WITH THE COMPLEX CATALYST SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2004-01-14 EP disclosed
US-5012017-A Peroxide oxidation of halogenated phenoxyphenones to phenoxyophenyl esters, then conversions to phenoxyphenols DOWELANCO (US) 1991-04-30 US disclosed
WO-1990009979-A1 METHODS FOR THE PREPARATION OF BROMINATED INTERMEDIATES THE DOW CHEMICAL COMPANY (US) 1990-09-07 WO disclosed
CN-1045094-A The method for preparing the bromination intermediate DOW CHEMICAL CO (US) 1990-09-05 CN disclosed
EP-0384043-A2 Methods for the preparation of brominated intermediates THE DOW CHEMICAL COMPANY (US) 1990-08-29 EP disclosed
US-4607051-A Carbamic acid compound and use as a pesticide HOFFMANN-LA ROCHE INC. (US) 1986-08-19 US disclosed
US-4413010-A Carbamic acid esters and use as pesticides HOFFMANN-LA ROCHE INC. (US) 1983-11-01 US disclosed