Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 17/20 | 0.54 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 17/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050098 | 0.93 | OPRM1 (0.48) | OPRM1OGFRL1OPRL1OPRK1 | |
| SCHEMBL1305494 | 0.82 | OPRM1 (0.58) | OPRM1OGFRL1OPRL1OPRK1OPRD1 | |
| SCHEMBL4053562 | 0.77 | OPRM1 (0.55) | OPRM1OGFRL1OPRL1OPRK1OPRD1 | |
| SCHEMBL4049842 | 0.73 | OPRM1 (0.48) | OPRM1OGFRL1OPRL1OPRK1OPRD1 | |
| Citric Acid SCHEMBL1303790 | 0.72 | OPRM1 (0.47) | OPRM1OGFRL1OPRL1OPRK1OPRD1 | |
| SCHEMBL4047623 | 0.71 | OPRM1 (0.49) | OPRM1OGFRL1OPRL1OPRK1 | |
| SCHEMBL1304619 | 0.71 | OPRM1 (0.60) | OPRM1OGFRL1OPRL1OPRK1OPRD1 | |
| Sulfuric Acid SCHEMBL5651389 | 0.71 | OPRM1 (0.48) | OPRM1OGFRL1OPRL1OPRK1 | |
| SCHEMBL682213 | 0.70 | OPRM1 (1.00) | OPRM1OGFRL1OPRL1OPRK1OPRD1 | |
| SCHEMBL1119635 | 0.70 | OPRL1 (0.56) | OPRM1OPRL1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697379-B1 | SPIROCYCLIC CYCLOHEXANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-03-25 | — | — | EP | claimed |