Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12026428 | 0.80 | KDM2B (0.37) | DPP4DPP7MAP4K4HRH3 | |
| SCHEMBL21476048 | 0.80 | KDM2B (0.37) | DPP4DPP7MAP4K4HRH3 | |
| SCHEMBL749969 | 0.80 | KDM2B (0.37) | DPP4DPP7MAP4K4HRH3 | |
| SCHEMBL21130809 | 0.78 | HRH3 (0.35) | DPP4HRH3 | |
| SCHEMBL3822046 | 0.78 | HRH3 (0.35) | DPP4HRH3 | |
| SCHEMBL21204683 | 0.74 | DPP4 (0.32) | DPP4DPP7HRH3 | |
| SCHEMBL21779876 | 0.73 | HRH3 (0.43) | HRH3 | |
| SCHEMBL21779953 | 0.73 | HRH3 (0.43) | HRH3 | |
| SCHEMBL15018879 | 0.71 | HRH3 (0.44) | HRH3 | |
| SCHEMBL16279294 | 0.71 | HRH3 (0.44) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-A1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | F.HOFFMANN-LA ROCHE AG (CH) | 2009-03-25 | — | — | EP | disclosed |
| WO-2008000645-A1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-01-03 | — | — | WO | disclosed |