Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28941990 | 0.87 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1MAPTTSHRATM | |
| SCHEMBL14343529 | 0.84 | LMNA (0.53) | SMN1; SMN2ALDH1A1MAPTTSHRKDM4E | |
| SCHEMBL28941997 | 0.84 | MAPT (0.51) | SMN1; SMN2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL28941994 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1MAPTTSHRATM | |
| SCHEMBL28926828 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1MAPTTSHRATM | |
| SCHEMBL28941993 | 0.83 | MAPT (0.50) | SMN1; SMN2ALDH1A1MAPTTSHRATM | |
| SCHEMBL30363504 | 0.83 | PKM (0.50) | SMN1; SMN2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL28941981 | 0.83 | PKM (0.50) | SMN1; SMN2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL28963867 | 0.83 | NPC1 (0.51) | ALDH1A1MAPTKDM4ENPSR1NPC1 | |
| SCHEMBL28941998 | 0.82 | NPSR1 (0.52) | SMN1; SMN2ALDH1A1MAPTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109467639-B | Thermo-sensitive poly (acetamido ethyl acrylate-co-benzoyl amino ethyl acrylate) and preparation method thereof | 河北大学 | 2020-11-24 | — | — | CN | claimed |
| CN-115650885-A | Preparation method of N-acyl-2-amino acrylate | 新乡学院 | 2023-01-31 | — | — | CN | disclosed |
| CN-109467639-B | Thermo-sensitive poly (acetamido ethyl acrylate-co-benzoyl amino ethyl acrylate) and preparation method thereof | 河北大学 | 2020-11-24 | — | — | CN | disclosed |
| CN-104817486-B | A kind of synthetic method of ramipril intermediate | 浙江工业大学 | 2018-05-22 | — | — | CN | disclosed |