Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL7123846 | 1.00 | — | — | |
| Ethylamine SCHEMBL28226268 | 0.89 | — | — | |
| Methylamine SCHEMBL28253427 | 0.88 | — | — | |
| SCHEMBL705113 | 0.88 | — | — | |
| Butylamine SCHEMBL28651336 | 0.87 | DNM1 (0.42) | — | |
| Phosphine SCHEMBL27912494 | 0.85 | — | — | |
| Ammonia Solution, Strong SCHEMBL28036698 | 0.85 | — | — | |
| Water SCHEMBL27487507 | 0.85 | — | — | |
| Ethylenediamine SCHEMBL54975 | 0.84 | DNM1 (0.38) | — | |
| SCHEMBL233156 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7527870-B2 | Organosiloxane compositions | DOW CORNING CORPORATION (US) | 2009-05-05 | — | — | US | disclosed |
| EP-1620491-B1 | MOISTURE CURABLE ORGANOSILOXANE COMPOSITIONS | DOW CORNING (US) | 2007-04-25 | — | — | EP | disclosed |
| US-20060194067-A1 | Organosiloxane compositions | DOW SILICONES CORPORATION | 2006-08-31 | — | — | US | disclosed |
| EP-1620491-A1 | MOISTURE CURABLE ORGANOSILOXANE COMPOSITIONS | Dow Corning Corporation (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004094503-A1 | MOISTURE CURABLE ORGANOSILOXANE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2004-11-04 | — | — | WO | disclosed |