Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 9/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butylamine SCHEMBL961752 | 0.93 | DNM1 (0.42) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Ethylamine SCHEMBL9171476 | 0.92 | DNM1 (0.33) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL960346 | 0.91 | DNM1 (0.52) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Methylamine SCHEMBL302747 | 0.90 | ADRB2 (0.33) | TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL274371 | 0.89 | — | — | |
| Ammonia Solution, Strong SCHEMBL28015905 | 0.87 | TSHR (0.33) | TSHR | |
| SCHEMBL3674575 | 0.87 | TSHR (0.33) | TSHR | |
| Ethylenediamine SCHEMBL4047330 | 0.84 | — | — | |
| Ethylenediamine SCHEMBL7123846 | 0.84 | — | — | |
| Butylamine SCHEMBL28651336 | 0.83 | DNM1 (0.42) | DNM1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 828 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016331-B | Preparation method of exogenous excitation color-changeable electrophoretic particles and electrophoretic display microcell | 广州奥翼电子科技股份有限公司 | 2022-12-09 | — | — | CN | claimed |
| CN-115181324-A | Sodium bicarbonate microcapsule and preparation method thereof | 广东省本奇环保新材料有限公司 | 2022-10-14 | — | — | CN | claimed |
| CN-115044175-A | Degradable master batch, preparation method thereof and mulching film containing degradable master batch | 中国农业科学院农业环境与可持续发展研究所 | 2022-09-13 | — | — | CN | claimed |
| CN-115028913-A | Heat-preservation mulching film master batch, preparation method thereof and mulching film containing master batch | 中国农业科学院农业环境与可持续发展研究所 | 2022-09-09 | — | — | CN | claimed |
| CN-114990897-A | Ceramic silicon rubber glass fiber coated fabric and preparation method thereof | 湖北晟特新材料有限公司 | 2022-09-02 | — | — | CN | claimed |
| CN-114604852-A | Preparation method of novel linear graphite alkyne serving as supercapacitor negative electrode material | 深圳市翔丰华科技股份有限公司 | 2022-06-10 | — | — | CN | claimed |
| CN-114520345-A | Integrated electrode frame with bipolar plate and preparation and application thereof | 中国科学院大连化学物理研究所 | 2022-05-20 | — | — | CN | claimed |
| CN-114437626-A | Polyurethane waterproof coating and preparation method thereof | 科顺防水科技股份有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-112226197-B | Modified silicone sealant for treating asphalt pavement cracks and preparation method thereof | 重庆重交再生资源开发股份有限公司 | 2022-04-22 | — | — | CN | claimed |
| CN-110841490-B | Composite membrane and preparation method and application thereof | 江苏久膜高科技股份有限公司 | 2022-02-18 | — | — | CN | claimed |
| CN-110743372-A | Device and process for preparing methanol and butyl acetate | 南京九思高科技有限公司 | 2020-02-04 | — | — | CN | claimed |
| CN-110698864-A | 5G PPS film and preparation method thereof | 兰飞 | 2020-01-17 | — | — | CN | claimed |
| CN-110652986-A | Reticular magnetic Fe3O4Preparation method and application of/GO/ZnO catalyst | 李克非 | 2020-01-07 | — | — | CN | claimed |
| CN-110614079-A | Preparation method and application of net-shaped magnetic graphene oxide | 李克非 | 2019-12-27 | — | — | CN | claimed |
| CN-110551429-A | method for improving adhesion of high-humidity-resistant coating adhesive of anhydride-epoxy system | GUANGDONG TGPM AUTOMOTIVE IND GROUP CO LTD | 2019-12-10 | — | — | CN | claimed |
| US-9757944-B2 | Liquid jet head and method for producing same, and liquid jet apparatus and image forming apparatus | RICOH COMPANY, LTD. (JP) | 2017-09-12 | — | — | US | claimed |
| EP-3145723-A1 | LIQUID JET HEAD AND METHOD FOR PRODUCING SAME, AND LIQUID JET APPARATUS AND IMAGE FORMING APPARATUS | Ricoh Company, Ltd. (JP) | 2017-03-29 | — | — | EP | claimed |
| US-20170043580-A1 | LIQUID JET HEAD AND METHOD FOR PRODUCING SAME, AND LIQUID JET APPARATUS AND IMAGE FORMING APPARATUS | RICOH COMPANY, LTD. (JP) | 2017-02-16 | — | — | US | claimed |
| WO-2015178010-A1 | LIQUID JET HEAD AND METHOD FOR PRODUCING SAME, AND LIQUID JET APPARATUS AND IMAGE FORMING APPARATUS | RICOH COMPANY, LTD. (JP) | 2015-11-26 | — | — | WO | claimed |
| EP-1036807-B1 | Curable composition | KANEKA CORP (JP) | 2007-12-12 | — | — | EP | claimed |