Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751577 | 0.65 | ATAD2 (0.33) | RPS6KA3GDAALDH1A1MAPT | |
| SCHEMBL28816416 | 0.62 | GDA (0.30) | GDA | |
| SCHEMBL29572751 | 0.55 | IDH1 (0.30) | — | |
| SCHEMBL31214551 | 0.54 | MAPT (0.62) | RPS6KA3GDAALDH1A1MAPT | |
| SCHEMBL8259690 | 0.53 | ALDH1A1 (0.38) | GDAALDH1A1MAPT | |
| SCHEMBL9008314 | 0.53 | GDA (0.71) | GDAALDH1A1MAPT | |
| SCHEMBL20706 | 0.53 | — | — | |
| SCHEMBL9062085 | 0.53 | IDH1 (0.44) | GDAALDH1A1MAPT | |
| SCHEMBL30107638 | 0.53 | — | — | |
| SCHEMBL31490467 | 0.52 | TYMP (0.56) | GDA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108904505-A | 6,8- of one kind xanthine class compound is preparing the application in anti-hepatic-B virus medicine | 中山大学 | 2018-11-30 | — | — | CN | claimed |
| CN-108904505-A | 6,8- of one kind xanthine class compound is preparing the application in anti-hepatic-B virus medicine | 中山大学 | 2018-11-30 | — | — | CN | disclosed |
| CN-103340921-A | Traditional Chinese medicine for treating insufficiency of both the spleen and the kidney and preparation method thereof | WUHAN JIANHENG PHARMACEUTICAL CO LTD | 2013-10-09 | — | — | CN | disclosed |
| EP-1562589-B1 | DIAMINOTRIAZOLES USEFUL AS INHIBITORS OF PROTEIN KINASES | VERTEX PHARMA (US) | 2009-01-07 | — | — | EP | disclosed |
| CN-1919859-A | Synthesis of 2'-deoxy-l-nucleosides | PHARMASSET LTD (US) | 2007-02-28 | — | — | CN | disclosed |
| CN-1919858-A | Synthesis of 2'-deoxy-l-nucleosides | PHARMASSET LTD (US) | 2007-02-28 | — | — | CN | disclosed |
| CN-1919860-A | Synthesis of 2'-deoxy-l-nucleosides | PHARMASSET LTD (US) | 2007-02-28 | — | — | CN | disclosed |
| CN-1216614-C | Pharmaceutical composition for delaying chronic renal failure | XUANW HOSPITAL CAPITAL MEDICAL (CN) | 2005-08-31 | — | — | CN | disclosed |
| CN-1423654-A | Synthesis of 2' -deoxy-L-nucleosides | PHARMASSET LTD (US) | 2003-06-11 | — | — | CN | disclosed |
| CN-1363375-A | Pharmaceutical composition for delaying chronic renal failure | XUANW HOSPITAL CAPITAL MEDICAL (CN) | 2002-08-14 | — | — | CN | disclosed |
| WO-1999042093-A3 | ANTAGONISTS OF A2B HUMAN ADENOSINE RECEPTORS | UNIV VIRGINIA (US) | 1999-10-28 | — | — | WO | disclosed |
| CN-1045778-C | Novel chemical compounds having PDE-IV inhibition activity | EURO CELTIQUE SA (LU) | 1999-10-20 | — | — | CN | disclosed |
| WO-1999042093-A2 | ANTAGONISTS OF A2B HUMAN ADENOSINE RECEPTORS | UNIVERSITY OF VIRGINIA (US) | 1999-08-26 | — | — | WO | disclosed |
| CN-1125445-A | Novel compounds having P.DE-IV inhibitory activity | EURO CELTIQUE SA (LU) | 1996-06-26 | — | — | CN | disclosed |