Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.46 |
| ▸ | CNR2 | P34972 | 7/20 | 0.46 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13691225 | 1.00 | CNR1 (0.46) | CNR1CNR2CTSLBACE1HPGDS | |
| SCHEMBL13690527 | 0.90 | CNR1 (0.47) | CNR1CNR2CTSLHPGDS | |
| SCHEMBL4057194 | 0.87 | CNR1 (0.60) | CNR1CNR2RAB9A | |
| SCHEMBL4054720 | 0.86 | CNR1 (0.52) | CNR1CNR2BACE1KDM4CRAB9A | |
| SCHEMBL4056091 | 0.85 | CNR1 (0.59) | CNR1CNR2RAB9A | |
| SCHEMBL4051609 | 0.80 | CNR1 (0.48) | CNR1CNR2KDM4CRAB9AMAPT | |
| SCHEMBL13690956 | 0.80 | CNR1 (0.48) | CNR1CNR2KDM4CRAB9AMAPT | |
| SCHEMBL4047757 | 0.79 | CNR1 (0.45) | CNR1CNR2 | |
| SCHEMBL4054772 | 0.79 | CNR1 (0.48) | CNR1CNR2CTSL | |
| SCHEMBL4057370 | 0.79 | CNR1 (0.47) | CNR1CNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |